Evidence map›Paper›PMID 31401647›Full record

ArticlePediatric research2020

How does gestational age affect growth and body composition of preterm twins?

Nadia Liotto, Paola Roggero, Francesca Giuliani, Daniela Morniroli, Maria L Giannì, Beatrice Bracco, Camilla Menis, Anna Orsi, Pasqua Piemontese, Orsola Amato and 1 more

Open access · bronzeAbstract readComparative StudyTwin Study
PubMed Publisher
In one paragraph

Article in Pediatric research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Distinct birth size and postnatal growth patterns in preterm twins and singletons: an etiology-based analysis from the INTERPRACTICE-21Journal of perinatology : official journal of the California Perinatal Association · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Nadia LiottoNICU Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy. nadia.liotto@policlinico.mi.it.ORCID http://orcid.org/0000-0003-0425-5046
Paola RoggeroNICU Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Francesca GiulianiDepartment of Pediatrics, Ospedale Infantile Regina Margherita, Città della Salute e della Scienza di Torino, Torino, Italy.
Daniela MorniroliNICU Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Maria L GiannìNICU Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Beatrice BraccoNICU Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Camilla MenisNICU Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Anna OrsiNICU Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Pasqua PiemonteseNICU Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Orsola AmatoNICU Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Fabio MoscaNICU Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITUniversity of Milan · ITOspedale Regina Margherita · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTwins experience altered growth compared to singletons. The primary aim of this study was to compare growth and body composition (BC) of twin and singleton preterm infants from birth to 3 months according to gestational age (GA). Secondary aims were to evaluate the effect of chorionicity and mode of feeding on twins' BC.

methodsAnthropometric measurements and BC were performed at term and 3 months in preterm infants (GA < 37 weeks). Infants were categorized as: extremely, very, moderate and late preterm infants. Chorionicity was assigned as monochorionic, dichorionic or multichorionic. Mode of feeding was recorded as any human milk feeding vs formula feeding.

resultsFive hundred and seventy-six preterm infants were included (223 twins). Late-preterm twins were lighter and shorter at each study point; fat-free mass (FFM) was lower in these infants at each study point, compared to singletons. No differences were found between twins and singleton on the other category. Multichorionic infants had an FFM deficit compared to monochorionic and dichorionic at term, whereas no differences were found at 3 months. FFM at term was negatively associated with being twin and formula-fed.

conclusionsTwins and singletons born before 34 weeks' GA showed similar anthropometry and BC. Conversely, twin late-preterm infants showed different growth and BC compared to singletons.

Indexed as

Body CompositionChild DevelopmentTwins, DizygoticTwins, MonozygoticAge FactorsBirth WeightBottle FeedingBreast FeedingGestational AgeHumansInfantInfant FormulaInfant, Low Birth WeightInfant, NewbornInfant Nutritional Physiological PhenomenaInfant, Premature

Identifiers

PMID31401647
OpenAlexW2968808797

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.