Evidence map›Paper›PMID 31400300›Full record

ArticleActa tropica2019

High prevalence and genetic diversity of hepatitis B viruses in insectivorous bats from China.

Si-Cong Lei, Xiao Xiao, Jian-Wei Liu, Hui-Ju Han, Xiao-Qing Gong, Min Zhao, Li-Jun Wang, Xiang-Rong Qin, Xue-Jie Yu

Open access · greenAbstract read
In one paragraph

Article in Acta tropica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Si-Cong LeiState Key Laboratory of Virology, School of Health Sciences, Wuhan University, Wuhan, China. Electronic address: 459568134@qq.com.
Xiao XiaoState Key Laboratory of Virology, School of Health Sciences, Wuhan University, Wuhan, China. Electronic address: xiaoalltheway@gmail.com.
Jian-Wei LiuState Key Laboratory of Virology, School of Health Sciences, Wuhan University, Wuhan, China. Electronic address: liujw_2012@163.com.
Hui-Ju HanState Key Laboratory of Virology, School of Health Sciences, Wuhan University, Wuhan, China. Electronic address: 15098775325@163.com.
Xiao-Qing GongState Key Laboratory of Virology, School of Health Sciences, Wuhan University, Wuhan, China. Electronic address: 2017203050014@whu.edu.cn.
Min ZhaoState Key Laboratory of Virology, School of Health Sciences, Wuhan University, Wuhan, China. Electronic address: 963607765@qq.com.
Li-Jun WangState Key Laboratory of Virology, School of Health Sciences, Wuhan University, Wuhan, China. Electronic address: 631294938@qq.com.
Xiang-Rong QinState Key Laboratory of Virology, School of Health Sciences, Wuhan University, Wuhan, China. Electronic address: 490161337@qq.com.
Xue-Jie YuState Key Laboratory of Virology, School of Health Sciences, Wuhan University, Wuhan, China. Electronic address: yuxuejie@whu.edu.cn.
Wuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bats have been identified as the hosts of hepatitis B virus (HBV) in recent years and bats HBV can infect human hepatocyte. We investigated the prevalence and genetic diversity of HBV in bats in China. In this study, a total of 197 insectivorous bats belonging to 10 bat species were captured from karst caves in Mengyin County, Shandong Province and Xianning City, Hubei Province, China. PCR amplification indicated that in total 6.6% (13/197) bats were positive to HBVs. The HBV positive rate in bats was 7.1% (9/127) and 5.7% (4/70) in Shandong Province and Hubei Province, respectively. Phylogenetic analysis indicated that HBV from the two places were in the same cluster with 90.5%-99.5% homology, but distinct from bat HBVs from other places in China and other countries. We concluded that HBV was prevalent and genetic diversified in bats, supporting the hypothesis that bats may be the origin of primate hepadnaviruses.

Indexed as

Genetic VariationAnimalsChinaChiropteraElectrophoresis, Agar GelGenotypeHepatitis BHepatitis B virusHumansLiverPhylogenyPolymerase Chain ReactionPrevalenceBatHepadnaviridaeHepatitis B virus

Identifiers

PMID31400300
PMCPMC7092808
OpenAlexW2965437440

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.