Evidence map›Paper›PMID 31400198›Full record

ArticleJournal of the National Cancer Institute2020

Inactivation of Wild-Type p53 by Asparagine Endopeptidase in Glioblastoma: An Opportunity to Target the "Undruggable".

James J Manfredi

Open access · bronzeAbstract readEditorialComment
In one paragraph

Article in Journal of the National Cancer Institute, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

James J ManfrediDepartment of Oncological Sciences and the Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY.
Icahn School of Medicine at Mount Sinai · US

Funding

Role of the p53 C-terminal domain in tissue homeostasis, tumor suppression, and oncogenesisR01CA196234 · NCI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI MANFREDI, JAMES J, PRIVES, CAROL · 2016 to 2020
$3.0M
Tissue-specific tumor suppressor effects of p53R01CA200256 · NCI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI MANFREDI, JAMES J · 2015 to 2019
$2.3M
NCI NIH HHS R01 CA196234NCI NIH HHS R01 CA200256
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Brain NeoplasmsGlioblastomaAsparaginyl EndopeptidaseCysteine EndopeptidasesHumansTumor Suppressor Protein p53Asparaginyl EndopeptidaseCysteine EndopeptidasesTumor Suppressor Protein p53

Identifiers

PMID31400198
PMCPMC7156925
OpenAlexW2967480521

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.