Evidence map›Paper›PMID 31400074›Full record

ArticleJournal of biophotonics2019

Characterization of the human myocardium by optical coherence tomography.

Yu Gan, Theresa H Lye, Charles C Marboe, Christine P Hendon

Abstract read
In one paragraph

Article in Journal of biophotonics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Cardiac Adipose Tissue Segmentation via Image-Level Annotations.IEEE journal of biomedical and health informatics · 2023
    Article
  5. Automated analysis framework forBiomedical optics express · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Heterogeneity Measurement of Cardiac Tissues Leveraging Uncertainty Information from Image Segmentation.Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention · 2020
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yu GanDepartment of Electrical Engineering, Columbia University, New York, New York.
Theresa H LyeDepartment of Electrical Engineering, Columbia University, New York, New York.ORCID 0000-0001-7310-4220
Charles C MarboeDepartment of Pathology and Cell Biology, Columbia University Medical Center, New York, New York.
Christine P HendonDepartment of Electrical Engineering, Columbia University, New York, New York.

Funding

High resolution imaging of the myocardiumDP2HL127776 · NHLBI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI HENDON, CHRISTINE P · 2014 to 2019
$2.9M
Columbia University Fu Foundation SEAS Presidential FellowshipColumbia University Provost Award for Junior FacultyNational Science Foundation 1454365National Science Foundation EEC-1342273NHLBI NIH HHS DP2 HL127776NIH HHS 1DP2HL127776- 01
6 · The paper itself

Abstract

Imaging of cardiac tissue structure plays a critical role in the treatment and understanding of cardiovascular disease. Optical coherence tomography (OCT) offers the potential to provide valuable, high-resolution imaging of cardiac tissue. However, there is a lack of comprehensive OCT imaging data of the human heart, which could improve identification of structural substrates underlying cardiac abnormalities. The objective of this study was to provide qualitative and quantitative analysis of OCT image features throughout the human heart. Fifty human hearts were acquired, and tissues from all chambers were imaged with OCT. Histology was obtained to verify tissue composition. Statistical differences between OCT image features corresponding to different tissue types and chambers were estimated using analysis of variance. OCT imaging provided features that were able to distinguish structures such as thickened collagen, as well as adipose tissue and fibrotic myocardium. Statistically significant differences were found between atria and ventricles in attenuation coefficient, and between adipose and all other tissue types. This study provides an overview of OCT image features throughout the human heart, which can be used for guiding future applications such as OCT-integrated catheter-based treatments or ex vivo investigation of structural substrates.

Indexed as

Tomography, Optical CoherenceAgedCollagenFemaleFibrosisHeartHumansImage Processing, Computer-AssistedMaleMiddle AgedMyocardiumCollagencardiovascular diseaseshumansmyocardiumoptical coherencetomography

Identifiers

PMID31400074
PMCPMC7456394

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.