ArticleSurgical endoscopy2020
Resolution of anemia and improved quality of life following laparoscopic hiatal hernia repair.
Article in Surgical endoscopy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 15 citations in OpenAlex.
- Cameron Lesions: Endoscopic Characteristics, Clinical Profile, and Therapeutic Implications-A Retrospective Study of 43 Patients.Diagnostics (Basel, Switzerland) · 2026Article
- Causal association between gastroesophageal reflux disease and anemia: Mendelian randomization analysis.Annals of medicine and surgery (2012) · 2026Article
- Quality of life after primary antireflux surgery: an analysis by primary indication.Surgical endoscopy · 2025Article
- The effect of frailty and age on outcomes in elective paraesophageal hernia repair.Surgical endoscopy · 2023Article
- Resolution and recurrence of anemia following repair of paraesophageal hernias.Surgical endoscopy · 2023Article
- Surgical treatment of anaemia - is it possible? Large hiatal hernia as a cause of severe iron-deficiency anaemia.Przeglad gastroenterologiczny · 2022Article
- Patients with ineffective esophageal motility benefit from laparoscopic antireflux surgery.Surgical endoscopy · 2021Article
- Paraesophageal hernia and iron deficiency anemia: Mechanisms, diagnostics and therapy.World journal of gastrointestinal surgery · 2021Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCameron lesions (CL) are common complications of large hiatal hernia (HH) disease and are known to result in chronic blood loss with resultant microcytic anemia. There is support in the literature that repair of HH may lead to resolution of CL and restore normal hemoglobin levels. This study aimed to determine the impact of elective HH repair on resolution of anemia and the quality of life (QOL) in patients with CL.
methodA single-institution, retrospective review analyzed all patients with history of CL or anemia (hemoglobin < 12.0 gm/dl in women, < 13.5 gm/dl in men) who underwent HH repair from January 2012 to May 2019. Four validated surveys were used to assess QOL: Reflux Symptom Index (RSI), gastroesophageal reflux disease health-related QOL (GERD-HRQL), laryngopharyngeal reflux health-related QOL (LPR-HRQL), and QOL and swallowing disorders (SWAL) survey. History of iron supplements and perioperative hemoglobin were also noted.
resultNinety-six patients were included in this study. The mean age was 67.4 ± 10.8 years and 79% of patients were female. CL were endoscopically identified in 61.5% of patients preoperatively, and the rest of the patients experienced anemia of undiagnosed origin but had a high suspicion for CL. Mean follow-up after HH repair was 17.3 months (range, 1 month-5 years). Mean preoperative hemoglobin was 11.01 ± 2.9 gm/dl and 13.23 ± 1.6 gm/dl postoperatively (p < 0.01). Forty-two (73.7%) patients had resolution of anemia during follow-up and 94.5% stopped supplemental oral iron. Finally, QOL scores significantly improved after surgical intervention: RSI (63%), GERD-HRQL (77%), LPR-HRQOL (72%), and SWAL (13%).
conclusionElective HH repair in patients with chronic anemia secondary to CL may potentially resolve CL and anemia and contribute to significant QOL improvements. Future studies will prospectively assess the resolution of CL with biochemical and endoscopic follow-up to confirm the preliminary findings of our analysis.
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