Evidence map›Paper›PMID 31399800›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2019

Joint EANM/ESNR and ESCMID-endorsed consensus document for the diagnosis of spine infection (spondylodiscitis) in adults.

Elena Lazzeri, Alessandro Bozzao, Maria Adriana Cataldo, Nicola Petrosillo, Luigi Manfrè, Andrej Trampuz, Alberto Signore, Mario Muto

Open access · bronzeAbstract readConsensus Statement
PubMed Publisher
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 4 pooled it
8.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 4 syntheses or guidelines pooled it, 91 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. EANM/SNMMI guideline/procedure standard for [European journal of nuclear medicine and molecular imaging · 2025
    Guideline
  4. Diagnostic performance ofEuropean journal of nuclear medicine and molecular imaging · 2020
    Pooled it
  5. Article
  6. Review
  7. Diagnostic accuracy of radiolabelled-WBC scintigraphy in patients with antibiotic therapy.European journal of nuclear medicine and molecular imaging · 2026
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Infection and drug resistance · 2025
    Article
  14. Article
  15. Review
  16. [Antibiotics (Basel, Switzerland) · 2024
    Article
  17. Article
  18. Review
  19. Imaging of musculoskeletal tuberculosis.The British journal of radiology · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 5 countries.

Elena LazzeriEuropean Association of Nuclear Medicine (EANM), Vienna, Austria. e_lazzeri@hotmail.com.ORCID http://orcid.org/0000-0003-0185-1424
Alessandro BozzaoEuropean Society of Neuroradiology (ESNR), Leuven, Belgium.
Maria Adriana CataldoEuropean Society of Clinical Microbiology and Infectious Diseases (ESCMID), Basel, Switzerland.
Nicola PetrosilloEuropean Society of Clinical Microbiology and Infectious Diseases (ESCMID), Basel, Switzerland.
Luigi ManfrèEuropean Society of Neuroradiology (ESNR), Leuven, Belgium.
Andrej TrampuzEuropean Society of Clinical Microbiology and Infectious Diseases (ESCMID), Basel, Switzerland.
Alberto SignoreEuropean Association of Nuclear Medicine (EANM), Vienna, Austria.
Mario MutoRegional Center of Nuclear Medicine, Azienda Ospedaliero Universitaria Pisana, 56123 Via Roma, 67, Pisa, Italy.
European Society of Anaesthesiology · BEIstituto Nazionale per le Malattie Infettive Lazzaro Spallanzani · ITEuropean Association of Nuclear Medicine · ATEuropean Society of Clinical Microbiology and Infectious Diseases · CHOspedale Antonio Cardarelli · ITUniversity of Pisa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeDiagnosis of spondylodiscitis (SD) may be challenging due to the nonspecific clinical and laboratory findings and the need to perform various diagnostic tests including serologic, imaging, and microbiological examinations. Homogeneous management of SD diagnosis through international, multidisciplinary guidance would improve the sensitivity of diagnosis and lead to better patient outcome.

methodsAn expert specialist team, comprising nuclear medicine physicians appointed by the European Association of Nuclear Medicine (EANM), neuroradiologists appointed by the European Society of Neuroradiology (ESNR), and infectious diseases specialists appointed by the European Society of Clinical Microbiology and Infectious Diseases (ESCMID), reviewed the literature from January 2006 to December 2015 and proposed 20 consensus statements in answer to clinical questions regarding SD diagnosis. The statements were graded by level of evidence level according to the 2011 Oxford Centre for Evidence-based Medicine criteria and included in this consensus document for the diagnosis of SD in adults. The consensus statements are the result of literature review according to PICO (P:population/patients, I:intervention/indicator, C:comparator/control, O:outcome) criteria. Evidence-based recommendations on the management of adult patients with SD, with particular attention to radiologic and nuclear medicine diagnosis, were proposed after a systematic review of the literature in the areas of nuclear medicine, radiology, infectious diseases, and microbiology.

resultsA diagnostic flow chart was developed based on the 20 consensus statements, scored by level of evidence according to the Oxford Centre for Evidence-based Medicine criteria.

conclusionsThis consensus document was developed with a final diagnostic flow chart for SD diagnosis as an aid for professionals in many fields, especially nuclear medicine physicians, radiologists, and orthopaedic and infectious diseases specialists.

Indexed as

DocumentationNuclear MedicineSocieties, MedicalAdultDiscitisEuropeHumansImagingInfection diagnosisSpinal infectionSpondylodiscitisVertebral infection

Identifiers

PMID31399800
OpenAlexW2968511373

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.