Evidence map›Paper›PMID 31399786›Full record

ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2019

Postoperative pain following Descemet membrane endothelial keratoplasty (DMEK): a prospective study.

Johannes Loeser, Julian Schwemmer, Antoniu-Oreste Gostian, Magdalena Gostian, Björn Bachmann, Claus Cursiefen, Ludwig M Heindl

Abstract read
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In one paragraph

Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Johannes LoeserDepartment of Anaesthesiology and Intensive Care Medicine, University of Cologne, Cologne, Germany.
Julian SchwemmerDepartment of Anaesthesiology and Intensive Care Medicine, University of Cologne, Cologne, Germany.
Antoniu-Oreste GostianDepartment of Otolaryngology, Head & Neck Surgery, University Hospital Erlangen, Erlangen, Germany.
Magdalena GostianDepartment of Anaesthesiology and Intensive Care Medicine, University of Cologne, Cologne, Germany.
Björn BachmannDepartment of Ophthalmology, University of Cologne, Kerpener Strasse 62, 50924, Cologne, Germany.
Claus CursiefenDepartment of Ophthalmology, University of Cologne, Kerpener Strasse 62, 50924, Cologne, Germany.
Ludwig M HeindlDepartment of Ophthalmology, University of Cologne, Kerpener Strasse 62, 50924, Cologne, Germany. ludwig.heindl@uk-koeln.de.ORCID http://orcid.org/0000-0002-4413-6132
University of Cologne · DEUniversitätsklinikum Erlangen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate postoperative pain following Descemet membrane endothelial keratoplasty (DMEK).

methodsSeventy-one patients completed perioperatively (day before surgery, day of surgery, 1st, 2nd, and 3rd day after surgery) four different questionnaires (a hospital internal protocol, QUIPS, PainDETECT®, and SF36) regarding their pain and other clinical parameters such as constipation, tiredness, vertigo, sleep disorders, concentration disorders, nausea, and emesis. All standardised questionnaires were evaluated to quantify average pain intensity as well as maximum pain intensity (NRS, 0 [no pain] to 10 [maximal pain], respectively). Analgesic treatment and intraocular pressure (IOP) during the perioperative stay were documented.

resultsMean average pain intensity was 0.70 ± 1.64 before surgery, 1.97 ± 2.05 on the day of surgery, 1.39 ± 1.68 on day 1, 0.87 ± 1.36 on day 2, and 0.81 ± 1.24 on day 3 after surgery. Maximum pain intensity was 0.65 ± 1.81 before surgery, 3.35 ± 2.98 on the day of surgery, 2.68 ± 2.99 on day 1, 1.49 ± 2.15 on day 2, and 1.26 ± 2.02 on day 3 after surgery. During the first three postoperative days, over 90% of the patients stated no or well tolerable pain. Eighty-three percent had postoperatively no need for analgesics at all. On the first two postoperative days, maximum IOP correlated significantly with reported increased maximum pain intensity (p = 0.043 and p = 0.029, respectively). All patients had very little problems with constipation, tiredness, vertigo, sleep disorder, concentration disorders, nausea, and emesis.

conclusionsDMEK is associated with low postoperative pain intensity. Strong pain increase may indicate IOP elevation and should be further investigated and treated. CLINICAL

trial registrationGerman Clinical Trial Register (DRKS00013995).

Indexed as

Visual AcuityAdultAgedAged, 80 and overCorneal DiseasesDescemet Stripping Endothelial KeratoplastyFemaleFollow-Up StudiesHumansIntraocular PressureMaleMiddle AgedPain MeasurementPostoperative PainPrognosisProspective StudiesCorneaDescemet membrane endothelial keratoplasty (DMEK)KeratoplastyPainQuality managementTransplantation

Identifiers

PMID31399786
OpenAlexW2967941195

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.