ArticleClinical neuroradiology2020
Associations Between Diffusion Dynamics and Functional Outcome in Acute and Early Subacute Ischemic Stroke.
Article in Clinical neuroradiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Diffusion kurtosis imaging in acute ischemic stroke: A systematic review of clinical correlations and prognostic utility.Neuroradiology · 2025Pooled it
- MRI whole-lesion texture analysis on ADC maps for the prognostic assessment of ischemic stroke.BMC medical imaging · 2022Article
- Predicting cancer malignancy and proliferation in glioma patients: intra-subject inter-metabolite correlation analyses using MRI and MRSI contrast scans.Quantitative imaging in medicine and surgery · 2021Article
- Article
- Effect of Conscious Sedation vs. General Anesthesia on Outcomes in Patients Undergoing Mechanical Thrombectomy for Acute Ischemic Stroke: A Prospective Randomized Clinical Trial.Frontiers in neurology · 2020Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
purposeThe current study aimed to investigate the associations between diffusion dynamics of ischemic lesions and clinical functional outcome of acute and early subacute stroke. MATERIAL AND
methodsA total of 80 patients with first ever infarcts in the territory of the middle cerebral artery underwent multi-b-values diffusion-weighted imaging and diffusion kurtosis imaging. Multiple diffusion parameters were generated in postprocessing using different diffusion models. Long-term functional outcome was evaluated with modified Rankin scale (mRS) at 6 months post-stroke. Good functional outcome was defined as mRS score ≤ 2 and poor functional outcome was defined as mRS score ≥ 3. Univariate analysis was used to compare the diffusion parameters and clinical features between patients with poor and good functional outcome. Significant parameters were further analyzed for correlations with functional outcome using partial correlation.
resultsIn univariate analyses, standard-b-values apparent diffusion coefficient (ADC
conclusionDiffusion dynamics are correlated with the clinical functional outcome of ischemic stroke. This correlation is independent of the effect of lesion volume and is specific to the time period between symptom onset and imaging. More effort is needed to further investigate the predictive value of diffusion-weighted imaging.
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Registered trials
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