Evidence map›Paper›PMID 31399725›Full record

ReviewNature reviews. Nephrology2020

Epidemiology, pathogenesis, treatment and outcomes of infection-associated glomerulonephritis.

Anjali A Satoskar, Samir V Parikh, Tibor Nadasdy

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Nephrology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
92citing papers in PubMed, 3 pooled it
9.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

92 citing papers in PubMed, 3 syntheses or guidelines pooled it, 163 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Pooled it
  4. Observational
  5. Article
  6. Article
  7. [Immune complex- and complement-mediated glomerulonephritides].Innere Medizin (Heidelberg, Germany) · 2026
    Review
  8. [Approach to suspected glomerulonephritis].Innere Medizin (Heidelberg, Germany) · 2026
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Observational
  18. Article
  19. Article
  20. Article

32 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Anjali A SatoskarDepartment of Pathology, Wexner Medical Center, The Ohio State University, Columbus, OH, USA. anjali.satoskar@osumc.edu.ORCID http://orcid.org/0000-0002-3332-0161
Samir V ParikhDepartment of Internal Medicine, Wexner Medical Center, The Ohio State University, Columbus, OH, USA.
Tibor NadasdyDepartment of Pathology, Wexner Medical Center, The Ohio State University, Columbus, OH, USA.ORCID http://orcid.org/0000-0002-9209-642X
The Ohio State University Wexner Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For over a century, acute 'post-streptococcal glomerulonephritis' (APSGN) was the prototypical form of bacterial infection-associated glomerulonephritis, typically occurring after resolution of infection and a distinct infection-free latent period. Other less common forms of infection-associated glomerulonephritides resulted from persistent bacteraemia in association with subacute bacterial endocarditis and shunt nephritis. However, a major paradigm shift in the epidemiology and bacteriology of infection-associated glomerulonephritides has occurred over the past few decades. The incidence of APSGN has sharply declined in the Western world, whereas the number of Staphylococcus infection-associated glomerulonephritis (SAGN) cases increased owing to a surge in drug-resistant Staphylococcus aureus infections, both in the hospital and community settings. These Staphylococcus infections range from superficial skin infections to deep-seated invasive infections such as endocarditis, which is on the rise among young adults owing to the ongoing intravenous drug use epidemic. SAGN is markedly different from APSGN in terms of its demographic profile, temporal association with active infection and disease outcomes. The diagnosis and management of SAGN is challenging because of the lack of unique histological features, the frequently occult nature of the underlying infection and the older age and co-morbidities in the affected patients. The emergence of multi-drug-resistant bacterial strains further complicates patient treatment.

Indexed as

Age DistributionAnti-Bacterial AgentsAntihypertensive AgentsEndocarditis, BacterialFluid TherapyGlomerulonephritisHumansImmunosuppressive AgentsKidneyMethicillin-Resistant Staphylococcus aureusStaphylococcal InfectionsStaphylococcus aureusStaphylococcus epidermidisStreptococcal InfectionsStreptococcus pyogenesSubstance Abuse, IntravenousAnti-Bacterial AgentsAntihypertensive AgentsImmunosuppressive Agents

Identifiers

PMID31399725
OpenAlexW2968547283

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.