Evidence map›Paper›PMID 31399557›Full record

ArticleBlood cancer journal2019

Lymphopenia at diagnosis is highly prevalent in myelodysplastic syndromes and has an independent negative prognostic value in IPSS-R-low-risk patients.

Tobias Silzle, Sabine Blum, Esther Schuler, Jennifer Kaivers, Martina Rudelius, Barbara Hildebrandt, Norbert Gattermann, Rainer Haas, Ulrich Germing

Open access · goldAbstract read
In one paragraph

Article in Blood cancer journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 32 citations in OpenAlex.

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  14. Circulating lymphocyte trafficking to the bone marrow contributes to lymphopenia in myocardial infarction.American journal of physiology. Heart and circulatory physiology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Tobias SilzleDepartment of Medical Oncology and Hematology, Cantonal Hospital St. Gallen, St. Gallen, Switzerland.
Sabine BlumService and Central Laboratory of Hematology, University Hospital of Lausanne, Lausanne, Switzerland.
Esther SchulerDepartment of Hematology, Oncology, and Clinical Immunology, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
Jennifer KaiversDepartment of Hematology, Oncology, and Clinical Immunology, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
Martina RudeliusInstitute of Pathology, Ludwig-Maximilians-University Munich, Munich, Germany.
Barbara HildebrandtDepartment of Human Genetics, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
Norbert GattermannDepartment of Hematology, Oncology, and Clinical Immunology, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
Rainer HaasDepartment of Hematology, Oncology, and Clinical Immunology, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
Ulrich GermingDepartment of Hematology, Oncology, and Clinical Immunology, Heinrich Heine University Düsseldorf, Düsseldorf, Germany. Germing@med.uni-duesseldorf.de.
Heinrich Heine University Düsseldorf · DEKantonsspital St. Gallen · CHLudwig-Maximilians-Universität München · DEUniversity Hospital of Lausanne · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lymphopenia is associated with an increased mortality in several medical conditions. Its prognostic impact in myelodysplastic syndromes (MDS) is less well studied. Hence, we analyzed 1023 patients from the Düsseldorf MDS-registry with regard to the absolute lymphocyte count (ALC) at diagnosis. An ALC below the median of the population (1.2 × 10

Indexed as

AdolescentAdultAgedAged, 80 and overFemaleHumansLymphocyte CountLymphopeniaMaleMiddle AgedMyelodysplastic SyndromesNomogramsPrognosisRetrospective StudiesRisk FactorsSurvival Rate

Identifiers

PMID31399557
PMCPMC6689049
OpenAlexW2968465690

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.