ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2019
Neural Pattern Similarity Differentially Relates to Memory Performance in Younger and Older Adults.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 44 citations in OpenAlex.
- Trial
- Trait anxiety is associated with reduced reward-related replay at rest.Nature communications · 2025Article
- Neural effects of memory training to reduce false memories in older adults: Univariate and multivariate analyses.Neurobiology of aging · 2025Article
- Dissociative Effects of Age on Neural Differentiation at the Category and Item Levels.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- GABA levels decline with age: A longitudinal study.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Neural reinstatement of context memory in adults with autism spectrum disorder.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Neural Reinstatement of Overlapping Memories in Young and Older Adults.Journal of cognitive neuroscience · 2022Article
- Age-related dedifferentiation and hyperdifferentiation of perceptual and mnemonic representations.Neurobiology of aging · 2021Article
- Tracking Age Differences in Neural Distinctiveness across Representational Levels.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Oscillatory Mechanisms of Successful Memory Formation in Younger and Older Adults Are Related to Structural Integrity.Cerebral cortex (New York, N.Y. : 1991) · 2020Article
- Memory quality modulates the effect of aging on memory consolidation during sleep: Reduced maintenance but intact gain.NeuroImage · 2020Article
- Age-related neural dedifferentiation and cognition.Current opinion in behavioral sciences · 2020Article
- Article
- Comparison of Quality of Life among Patients with Oro-Hypopharyngeal Cancer after Tonsillectomy and Panscopy Using Transoral Robotic Surgery: A Pilot Study.Case reports in oncologyArticle
- Phase similarity between similar objects indicates representational merging across retrieval training but not sleep.Imaging neuroscience (Cambridge, Mass.)Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Age-related memory decline is associated with changes in neural functioning, but little is known about how aging affects the quality of information representation in the brain. Whereas a long-standing hypothesis of the aging literature links cognitive impairments to less distinct neural representations in old age ("neural dedifferentiation"), memory studies have shown that overlapping neural representations of different studied items are beneficial for memory performance. In an electroencephalography (EEG) study, we addressed the question whether distinctiveness or similarity between patterns of neural activity supports memory differentially in younger and older adults. We analyzed between-item neural pattern similarity in 50 younger (19-27 years old) and 63 older (63-75 years old) male and female human adults who repeatedly studied and recalled scene-word associations using a mnemonic imagery strategy. We compared the similarity of spatiotemporal EEG frequency patterns during initial encoding in relation to subsequent recall performance. The within-person association between memory success and pattern similarity differed between age groups: For older adults, better memory performance was linked to higher similarity early in the encoding trials, whereas young adults benefited from lower similarity between earlier and later periods during encoding, which might reflect their better success in forming unique memorable mental images of the joint picture-word pairs. Our results advance the understanding of the representational properties that give rise to subsequent memory, as well as how these properties may change in the course of aging.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.