Evidence map›Paper›PMID 31399514›Full record

ArticleThe Journal of biological chemistry2019

Systematic analysis of F-box proteins reveals a new branch of the yeast mating pathway.

Nambirajan Rangarajan, Claire L Gordy, Lauren Askew, Samantha M Bevill, Timothy C Elston, Beverly Errede, Jillian H Hurst, Joshua B Kelley, Joshua B Sheetz, Sara Kimiko Suzuki and 3 more

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Potassium starvation induces autophagy in yeast.The Journal of biological chemistry · 2020
    Article
  5. Article
  6. Regulation of large and small G proteins by ubiquitination.The Journal of biological chemistry · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Nambirajan RangarajanDepartment of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599.ORCID 0000-0002-8332-2448
Claire L GordyDepartment of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599.
Lauren AskewDepartment of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599.
Samantha M BevillDepartment of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599.
Timothy C ElstonDepartment of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599.
Beverly ErredeDepartment of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599.
Jillian H HurstDepartment of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599.ORCID 0000-0001-5079-9920
Joshua B KelleyDepartment of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599.
Joshua B SheetzDepartment of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599.ORCID 0000-0003-2052-1252
Sara Kimiko SuzukiDepartment of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599.ORCID 0000-0003-2225-7416
Natalie H ValentinDepartment of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599.
Everett YoungDepartment of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599.
Henrik G DohlmanDepartment of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 hdohlman@med.unc.edu.ORCID 0000-0003-2443-0729
University of North Carolina at Chapel Hill · US

Funding

Virology Research Program (Program 4)P30CA016086 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Deborah F. Tate · 1985 to 2026
$201.5M
SEEDING POSTDOCTORAL INNOVATORS IN RESEARCH &EDUCATIONK12GM000678 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DONALD T LYSLE, Kathryn Joanna Reissner · 1999 to 2026
$30.9M
Negative and positive feedback in cell signalingR35GM118105 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Henrik G. Dohlman · 2016 to 2026
$6.6M
PREDOCTORAL TRAINING IN PHARMACOLOGICAL SCIST32GM007040 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI NICHOLAS, ROBERT A · 1985 to 2019
$6.0M
Mathematical modeling of cellular signaling systemsR35GM127145 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Timothy C Elston · 2018 to 2026
$3.9M
Mechanisms of noise regulation in cell fate transitionsR01GM114136 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DOHLMAN, HENRIK G., ELSTON, TIMOTHY C · 2015 to 2018
$2.1M
NCI NIH HHS P30 CA016086NIGMS NIH HHS K12 GM000678NIGMS NIH HHS R01 GM114136NIGMS NIH HHS R35 GM118105NIGMS NIH HHS R35 GM127145NIGMS NIH HHS T32 GM007040
6 · The paper itself

Abstract

The mating pathway in yeast

Indexed as

Adaptor Proteins, Signal Transducingcdc42 GTP-Binding ProteinCell CycleClass III Phosphatidylinositol 3-KinasesEndosomesF-Box ProteinsGenes, Mating Type, FungalGTP-Binding Protein alpha Subunits, Gq-G11GTP-Binding Protein beta SubunitsGTP-Binding Protein gamma SubunitsMorphogenesisPheromonesSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSequence DeletionSignal TransductionAdaptor Proteins, Signal Transducingcdc42 GTP-Binding ProteinClass III Phosphatidylinositol 3-KinasesDia2 protein, S cerevisiaeF-Box ProteinsGPA1 protein, S cerevisiaeG-protein Beta gammaGTP-Binding Protein alpha Subunits, Gq-G11GTP-Binding Protein beta SubunitsGTP-Binding Protein gamma SubunitsPheromonesSaccharomyces cerevisiae ProteinsSTE5 protein, S cerevisiaeF-boxfungal matingG proteinmitogen-activated protein kinase (MAPK)pheromone signalingprotein sortingubiquitinyeast

Identifiers

PMID31399514
PMCPMC6779436
OpenAlexW2967850494

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.