Evidence map›Paper›PMID 31399476›Full record

ArticleCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2019

Association of BMI, Smoking, and Alcohol with Multiple Myeloma Mortality in Asians: A Pooled Analysis of More than 800,000 Participants in the Asia Cohort Consortium.

Tomotaka Ugai, Hidemi Ito, Isao Oze, Eiko Saito, Md Shafiur Rahman, Paolo Boffetta, Prakash C Gupta, Norie Sawada, Akiko Tamakoshi, Xiao Ou Shu and 26 more

Open access · bronzeAbstract read
In one paragraph

Article in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
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  12. Identification ofOncology research · 2023
    Article
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  14. The Association Between Smoking and Gut Microbiome in Bangladesh.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

36 authors at 20 institutions in 10 countries.

Tomotaka UgaiDivision of Cancer Epidemiology and Prevention, Department of Preventive Medicine, Aichi Cancer Center Research Institute, Nagoya, Japan.
Hidemi ItoDivision of Cancer Information and Control, Department of Preventive Medicine, Aichi Cancer Center Research Institute, Nagoya, Japan.ORCID 0000-0002-8023-4581
Isao OzeDivision of Cancer Epidemiology and Prevention, Department of Preventive Medicine, Aichi Cancer Center Research Institute, Nagoya, Japan.ORCID 0000-0002-0762-1147
Eiko SaitoDivision of Cancer Statistics, Integration Center for Cancer Control & Information Services, National Cancer Center, Tokyo, Japan.
Md Shafiur RahmanDepartment of Global Health Policy, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.ORCID 0000-0003-1911-6807
Paolo BoffettaIcahn School of Medicine at Mount Sinai, New York, New York.
Prakash C GuptaHealis Sekhsaria Institute for Public Health, Navi Mumbai, Maharashtra, India.ORCID 0000-0002-1265-0372
Norie SawadaEpidemiology and Prevention Group, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan.ORCID 0000-0002-9936-1476
Akiko TamakoshiDepartment of Public Health, Hokkaido University Graduate School of Medicine, Sapporo, Japan.ORCID 0000-0002-9761-3879
Xiao Ou ShuDivision of Epidemiology, Vanderbilt-Ingram Cancer Center, Vanderbilt Epidemiology Center, Nashville, Tennessee.
Woon-Puay KohHealth Services and Systems Research, Duke-NUS Medical School, Singapore, Singapore.
Yu-Tang GaoDepartment of Epidemiology, Shanghai Cancer Institute, Shanghai, China.
Atsuko SadakaneDepartment of Epidemiology, Radiation Effects Research Foundation, Hiroshima, Japan.ORCID 0000-0003-2190-0270
Ichiro TsujiDivision of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan.
Sue K ParkDepartment of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea.ORCID 0000-0001-5002-9707
Chisato NagataDepartment of Epidemiology and Preventive Medicine, Gifu University Graduate School of Medicine, Gifu, Japan.
San-Lin YouSchool of Medicine & Big Data Research Center, Fu Jen Catholic University, Taiwan.ORCID 0000-0002-3192-3356
Mangesh S PednekarHealis Sekhsaria Institute for Public Health, Navi Mumbai, Maharashtra, India.
Shoichiro TsuganeEpidemiology and Prevention Group, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan.
Hui CaiDivision of Epidemiology, Vanderbilt-Ingram Cancer Center, Vanderbilt Epidemiology Center, Nashville, Tennessee.
Jian-Min YuanDepartment of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania.
Yong-Bing XiangDepartment of Epidemiology, Shanghai Cancer Institute, Shanghai, China.
Kotaro OzasaDepartment of Epidemiology, Radiation Effects Research Foundation, Hiroshima, Japan.ORCID 0000-0002-5637-1383
Yasutake TomataDivision of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan.
Seiki KanemuraDivision of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan.ORCID 0000-0003-0454-0322
Yumi SugawaraDivision of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan.
Keiko WadaDepartment of Epidemiology and Preventive Medicine, Gifu University Graduate School of Medicine, Gifu, Japan.ORCID 0000-0002-5467-8592
Chien-Jen ChenGenomics Research Center, Academia Sinica, Taipei, Taiwan.
Keun-Young YooDepartment of Preventive Medicine, Seoul National University, Seoul, Korea.
Kee Seng ChiaSaw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.ORCID 0000-0002-0629-5570
Habibul AhsanDepartment of Public Health Sciences, University of Chicago, Chicago, Illinois.
Wei ZhengDivision of Epidemiology, Vanderbilt-Ingram Cancer Center, Vanderbilt Epidemiology Center, Nashville, Tennessee.
Manami InoueEpidemiology and Prevention Group, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan.ORCID 0000-0003-1276-2398
Daehee KangDepartment of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea.
John PotterFred Hutchinson Cancer Research Center, Seattle, Washington.ORCID 0000-0001-5439-1500
Keitaro MatsuoDivision of Cancer Epidemiology and Prevention, Department of Preventive Medicine, Aichi Cancer Center Research Institute, Nagoya, Japan. kmatsuo@aichi-cc.jp.ORCID 0000-0003-1761-6314
Aichi Cancer Center · JPTohoku University · JPPrevention Group · USVanderbilt University · USGifu University · JPHealis Sekhsaria Institute For Public Health · INNew Generation University College · ETRadiation Effects Research Foundation · JPShanghai Cancer Institute · CNChicago Department of Public Health · USDepartment of Health · IEFred Hutch Cancer Center · USFu Jen Catholic University · TWGenomics Research Center, Academia Sinica · TWHokkaido University · JPNational Cancer Center · USNational University of Singapore · SGSeoul National University · KRSingHealth · SGUniversity of Bologna · IT

Funding

Training CoreP42ES010349 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI NAVAS-ACIEN, ANA · 2000 to 2020
$53.6M
Pilot Program CoreP30ES027792 · NIEHS · UNIVERSITY OF CHICAGO · PI Gokhan M. Mutlu, Gail S Prins · 2017 to 2026
$13.6M
Prospective studies of cancer etiology and prevention in Shanghai and SingaporeR01CA144034 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI YUAN, JIAN-MIN · 2010 to 2014
$7.0M
Cohort Study of Cancer inhibitory Factors in MenR01CA082729 · NCI · VANDERBILT UNIVERSITY · PI SHU, XIAO-OU · 2001 to 2011
$6.3M
Shanghai Womens Health StudyUM1CA182910 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ZHENG, WEI · 2014 to 2018
$5.9M
DIETARY FACTORS IN THE ETIOLOGY OF CANCER IN SHANGHAIR01CA043092 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI YUAN, JIAN-MIN · 1987 to 2006
$5.8M
THE SINGAPORE COHORT STUDY OF DIET AND CANCERR01CA080205 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI YUAN, JIAN-MIN · 1999 to 2009
$5.3M
Shanghai Men's Health StudyUM1CA173640 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI SHU, XIAO-OU · 2013 to 2017
$4.9M
Cancer Risk Reduction and Diet: A Cohort Study of WomenR37CA070867 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ZHENG, WEI · 2009 to 2013
$4.7M
Cancer epidemiology cohorts in Shanghai and Singapore UM1CA182876 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI YUAN, JIAN-MIN · 2014 to 2018
$4.3M
Enhancement and Maintenance of the HEALS cohortR24ES028532 · NIEHS · UNIVERSITY OF CHICAGO · PI AHSAN, HABIBUL · 2017 to 2022
$1.7M
The Singapore Chinese Health StudyU01CA182876 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI YUAN, JIAN-MIN · 2019 to 2019
$150k
NCI NIH HHS R01 CA043092NCI NIH HHS R01 CA080205NCI NIH HHS R01 CA082729NCI NIH HHS R01 CA144034NCI NIH HHS R37 CA070867NCI NIH HHS U01 CA182876NCI NIH HHS UM1 CA173640NCI NIH HHS UM1 CA182876NCI NIH HHS UM1 CA182910NIEHS NIH HHS P30 ES027792NIEHS NIH HHS P42 ES010349NIEHS NIH HHS R24 ES028532
6 · The paper itself

Abstract

backgroundTo date, few epidemiologic studies have been conducted to elucidate lifestyle-related risk factors for multiple myeloma in Asia. We investigated the association of body mass index (BMI), smoking, and alcohol intake with the risk of multiple myeloma mortality through a pooled analysis of more than 800,000 participants in the Asia Cohort Consortium.

methodsThe analysis included 805,309 participants contributing 10,221,623 person-years of accumulated follow-up across Asia Cohort Consortium cohorts. HRs and 95% confidence intervals (95% CI) for the association between BMI, smoking, and alcohol at baseline and the risk of multiple myeloma mortality were assessed using a Cox proportional hazards model with shared frailty.

resultsWe observed a statistically significant dose-dependent association between BMI categories and the risk of multiple myeloma mortality (<18.5 kg/m

conclusionsThis study showed that excess body mass is associated with an increased risk of multiple myeloma mortality among Asian populations. In contrast, our results do not support an association between smoking or alcohol consumption and the risk of multiple myeloma mortality in Asian populations. IMPACT: This study provides important evidence on the association of BMI, smoking, and alcohol with the risk of multiple myeloma mortality in Asian populations.

Indexed as

Body Mass IndexAdolescentAdultAlcohol DrinkingAsiaCohort StudiesFemaleHumansMaleMultiple MyelomaSmokingYoung Adult

Identifiers

PMID31399476
PMCPMC7986478
OpenAlexW2968288119

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.