Evidence map›Paper›PMID 31399145›Full record

ReviewReproductive biology and endocrinology : RB&E2019

Reproductive functions of Kisspeptin/KISS1R Systems in the Periphery.

Yubin Cao, Zeping Li, Wenyu Jiang, Yan Ling, Haibin Kuang

Open access · goldAbstract readReview
In one paragraph

Review in Reproductive biology and endocrinology : RB&E, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 1 pooled it
11.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 1 synthesis or guideline pooled it, 103 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Functional Validation of a Novel <italic>PBX1</italic> Missense Variant in a 46,XY Girl.Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation · 2026
    Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Does the miR-105-1-Kisspeptin Axis Promote Ovarian Cell Functions?Reproductive sciences (Thousand Oaks, Calif.) · 2024
    Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yubin CaoDepartment of Physiology, Basic Medical College, Nanchang University, Nanchang, Jiangxi, 330006, People's Republic of China.
Zeping LiDepartment of Physiology, Basic Medical College, Nanchang University, Nanchang, Jiangxi, 330006, People's Republic of China.
Wenyu JiangDepartment of Physiology, Basic Medical College, Nanchang University, Nanchang, Jiangxi, 330006, People's Republic of China.
Yan LingDepartment of Obstetrics and Gynecology, Jiangxi Province People's Hospital, Nanchang, Jiangxi, 330006, People's Republic of China.
Haibin KuangDepartment of Physiology, Basic Medical College, Nanchang University, Nanchang, Jiangxi, 330006, People's Republic of China. kuanghaibin@ncu.edu.cn.ORCID http://orcid.org/0000-0003-4711-5449
Nanchang University · CNJiangxi Provincial People's Hospital · CN

Funding

National Natural Science Foundation of China 81860283 and 81671486
6 · The paper itself

Abstract

Kisspeptin and its G protein-coupled receptor KISS1R play key roles in mammalian reproduction due to their involvement in the onset of puberty and control of the hypothalamic-pituitary-gonadal axis. However, recent studies have indicated a potential role of extra-hypothalamic kisspeptin in reproductive function. Here, we summarize recent advances in our understanding of the physiological significance of kisspeptin/KISS1R in the peripheral reproductive system (including the ovary, testis, uterus, and placenta) and the potential role of kisspeptin/KISS1R in reproductive diseases. A comprehensive understanding of the expression, function, and potential molecular mechanisms of kisspeptin/KISS1R in the peripheral reproductive system will contribute to the diagnosis, treatment and prevention of reproductive diseases.

Indexed as

AnimalsFemaleKisspeptinsMaleOocytesOvaryOvulationPlacentaPregnancyReceptors, Kisspeptin-1SpermatogenesisTestisUterusKisspeptinsReceptors, Kisspeptin-1KISS1RKisspeptinOvaryPlacentaTestisUterus

Identifiers

PMID31399145
PMCPMC6689161
OpenAlexW2968989546

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.