ArticleHealth research policy and systems2019
A framework for value-creating learning health systems.
Article in Health research policy and systems, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 187 papers, 5 of them syntheses that pooled it.
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Who cites it
187 citing papers in PubMed, 5 syntheses or guidelines pooled it, 353 citations in OpenAlex.
- Learning health system for implementation, scale-up, and sustainment: a systematic review to consolidate guidance for improvement.Implementation science : IS · 2026Pooled it
- Organizational and Service Management Interventions for Improving the Patient Experience With Care: Systematic Review of the Effectiveness.The International journal of health planning and management · 2025Pooled it
- Implementation strategies and outcome measures for advancing learning health systems: a mixed methods systematic review.Health research policy and systems · 2023Pooled it
- Barriers and Facilitators to the Adoption of Evidence-Based Interventions for Adults Within Occupational and Physical Therapy Practice Settings: A Systematic Review.Archives of physical medicine and rehabilitation · 2023Pooled it
- Learning health systems using data to drive healthcare improvement and impact: a systematic review.BMC health services research · 2021Pooled it
- Toward a Smart Learning Health System: An Ontology-Based Framework.Learning health systems · 2026Article
- Development of the Learning Health Systems Toolkit: A Collaborative Effort to Bridge Concept and Practice.Learning health systems · 2026Article
- Leading Learning Health Systems: Strategies Used to Establish and Conduct a Learning Health System.Journal of general internal medicine · 2026Article
- Patient Engagement Activities and Infrastructure Among US Veterans Affairs National Research Networks.Journal of general internal medicine · 2026Article
- Promising Patient-Engagement Practices Used by National Research Networks at the US Veterans Health Administration: Perspectives of Veterans, Staff, and Research Leaders.Learning health systems · 2026Article
- Ethnocultural differences in symptom change, engagement, and adherence in internet-delivered cognitive behavioral therapy: A secondary analysis of a healthcare-embedded longitudinal study.Internet interventions · 2026Article
- ChiroSCOPE (Chiropractic Systematic Clinical Observation of Practice Evidence): preliminary evaluation of a web application for data collection within a clinical research network: a mixed methods pilot study.The Journal of the Canadian Chiropractic Association · 2026Article
- Exploring value-creating contexts in the capacity building of nursing managers: a reflective thematic analysis.BMC nursing · 2026Article
- Article
- A scoping review of outcome and outcome measure sets for adults with spinal cord injury, stroke, and traumatic brain injury.Journal of rehabilitation medicine · 2026Article
- Supporting Cultural and Learning Enablers for a Learning Health System (SCALE): A Program Theory Approach.Learning health systems · 2026Article
- Exploring Barriers, Enablers, and Strategies for Implementing Learning Health System Projects in Healthcare Organizations: A Multilevel Analysis in an Australian Setting.Learning health systems · 2026Article
- The HALO Model: A Learning Health System Framework for Artificial Intelligence.Learning health systems · 2026Article
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- Implementation of Outcome-Based Quality Improvement in Dutch Inflammatory Bowel Disease Centres.Digestive diseases and sciences · 2026Article
127 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInterest in value-based healthcare, generally defined as providing better care at lower cost, has grown worldwide, and learning health systems (LHSs) have been proposed as a key strategy for improving value in healthcare. LHSs are emerging around the world and aim to leverage advancements in science, technology and practice to improve health system performance at lower cost. However, there remains much uncertainty around the implementation of LHSs and the distinctive features of these systems. This paper presents a conceptual framework that has been developed in Canada to support the implementation of value-creating LHSs.
methodsThe framework was developed by an interdisciplinary team at the Institut national d'excellence en santé et en services sociaux (INESSS). It was informed by a scoping review of the scientific and grey literature on LHSs, regular team discussions over a 14-month period, and consultations with Canadian and international experts.
resultsThe framework describes four elements that characterise LHSs, namely (1) core values, (2) pillars and accelerators, (3) processes and (4) outcomes. LHSs embody certain core values, including an emphasis on participatory leadership, inclusiveness, scientific rigour and person-centredness. In addition, values such as equity and solidarity should also guide LHSs and are particularly relevant in countries like Canada. LHS pillars are the infrastructure and resources supporting the LHS, whereas accelerators are those specific structures that enable more rapid learning and improvement. For LHSs to create value, such infrastructures must not only exist within the ecosystem but also be connected and aligned with the LHSs' strategic goals. These pillars support the execution, routinisation and acceleration of learning cycles, which are the fundamental processes of LHSs. The main outcome sought by executing learning cycles is the creation of value, which we define as the striking of a more optimal balance of impacts on patient and provider experience, population health and health system costs.
conclusionsOur framework illustrates how the distinctive structures, processes and outcomes of LHSs tie together with the aim of optimising health system performance and delivering greater value in health systems.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.