ArticleBMC plant biology2019
A 4-bp deletion in the 5'UTR of TaAFP-B is associated with seed dormancy in common wheat (Triticum aestivum L.).
Article in BMC plant biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- Consensus genomic regions associated with multiple abiotic stress tolerance in wheat and implications for wheat breeding.Scientific reports · 2022Pooled it
- Genome-wide association and haplotype analyses reveal genetic architecture of seed dormancy in grain sorghum with implications for preharvest sprouting tolerance.The plant genome · 2026Article
- Beyond light signaling: the broad regulatory spectrum of AFPs in plant growth and development.Frontiers in plant science · 2026Review
- Antagonistic effects of selection on alleles associated with seed size and seed dormancy in wheat.Genome biology · 2025Article
- TaPP2C-a6 interacts with TaDOG1Ls and regulates seed dormancy and germination in wheat.Plant biotechnology journal · 2025Article
- Divergent molecular pathways govern temperature-dependent wheat stem rust resistance genes.Nature communications · 2025Article
- DOG1 controls dormancy independently of ABA core signaling kinases regulation by preventing AFP dephosphorylation through AHG1.Science advances · 2025Article
- Allelic variation of TaABI5-A4 significantly affects seed dormancy in bread wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- Genetic basis of an elite wheat cultivar Guinong 29 with harmonious improvement between multiple diseases resistance and other comprehensive traits.Scientific reports · 2024Article
- Article
- Genome-wide association mapping for pre-harvest sprouting in European winter wheat detects novel resistance QTL, pleiotropic effects, and structural variation in multiple genomes.The plant genome · 2024Article
- Transcriptome Analyses Show Changes in Gene Expression Triggered by a 31-bp InDel withinInternational journal of molecular sciences · 2023Article
- MiningFrontiers in plant science · 2023Article
- Exploring Breakthroughs in Three Traits Belonging to Seed Life.Plants (Basel, Switzerland) · 2022Review
- A 4 bp InDel in the Promoter of Wheat GeneFrontiers in plant science · 2022Article
- Genetic basis analysis of key Loci in 23 Yannong series wheat cultivars/lines.Frontiers in plant science · 2022Article
- Article
- Allele mining of TaGRF-2D gene 5'-UTR in Triticum aestivum and Aegilops tauschii genotypes.PloS one · 2020Article
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundAFP is a negative regulator of ABA signaling that promotes ABI5 protein degradation and weakens regulation of ABA signaling by targeting upstream genes of ABI5, and TaABI5 gene was seed-specific, and accumulated during wheat grain maturation and dormancy acquisition, which played an important role in seed dormancy; TaAFP has a conserved domain with AFP, so TaAFP may also play an important role in seed dormancy in wheat.
resultsTwo allelic variants of TaAFP were identified on chromosome 2BS in common wheat, and designated as TaAFP-B1a and TaAFP-B1b. Sequence analysis showed a 4-bp deletion in the 5'UTR region of TaAFP-B1b compared with TaAFP-B1a. Based on the 4-bp deletion, a co-dominant functional marker of TaAFP-B was developed and designated as AFPB. The genotype generating a 203-bp fragment (TaAFP-B1b) was more resistant to pre-harvest sprouting than the genotype producing a 207-bp fragment (TaAFP-B1a) in a test of 91 white-grained Chinese wheat cultivars and advanced lines. The average germination index(GI) values of TaAFP-B1a and that of TaAFP-B1b were 45.18 and 30.72%, respectively, indicating a significant difference (P < 0.001). Moreover, the 4-bp deletion located in the 5'UTR not only affected the transcription level of TaAFP-B but also affected the mRNA decay, reduced the translation level of GUS and tdTomatoER and GUS activity in wheat leaves of transient expression. The transcript expression and the mRNA half-life value of TaAFP-B1a in developing seeds and mature seeds were much higher than those of TaAFP-B1b.
conclusionWe identified a 4-bp InDel in the 5'UTR of TaAFP-B, which affected the mRNA transcription level, mRNA decay, translation levels of GUS and tdTomatoER, GUS activity, and was significantly associated with seed dormancy in common wheat. A functional marker was developed and validated based on this InDel.
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