ArticleMolecules (Basel, Switzerland)2019
Green Synthesis of Privileged Benzimidazole Scaffolds Using Active Deep Eutectic Solvent.
Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 65 citations in OpenAlex.
- Article
- Integrating green synthesis and liquid-liquid extraction of lidocaine in deep eutectic solvents.RSC medicinal chemistry · 2026Article
- Synthesis of Fluoroquinolones: Revisiting the Grohe Route in DES-Based Media.Pharmaceuticals (Basel, Switzerland) · 2026Article
- Organic Named Reactions in Green Deep Eutectic Solvents (DESs).Topics in current chemistry (Cham) · 2025Review
- Synthesis and SARs of benzimidazoles: insights into antimicrobial innovation (2018-2024).RSC advances · 2025Review
- Sustainable Synthesis of the Active Pharmaceutical Ingredient Atenolol in Deep Eutectic Solvents.International journal of molecular sciences · 2024Article
- Article
- A Review on the Use of Deep Eutectic Solvents in Protection Reactions.Molecules (Basel, Switzerland) · 2024Review
- How Can Deep Eutectic Systems Promote Greener Processes in Medicinal Chemistry and Drug Discovery?Pharmaceuticals (Basel, Switzerland) · 2024Review
- Alternative Assisted Extraction Methods of Phenolic Compounds Using NaDESs.Antioxidants (Basel, Switzerland) · 2023Review
- The Highly Efficient Synthesis of 1,2-Disubstituted Benzimidazoles Using Microwave Irradiation.Molecules (Basel, Switzerland) · 2022Article
- Deep Eutectic Solvents for Improving the Solubilization and Delivery of Dapsone.Pharmaceutics · 2022Article
- Molecular Dynamics Simulation of 2-Benzimidazolyl-Urea with DPPC Lipid Membrane and Comparison with a Copper(II) Complex Derivative.Membranes · 2021Article
- Lipase-Catalyzed Production of Sorbitol Laurate in a "2-in-1" Deep Eutectic System: Factors Affecting the Synthesis and Scalability.Molecules (Basel, Switzerland) · 2021Article
- Enzymatic Synthesis of Glucose Monodecanoate in a Hydrophobic Deep Eutectic Solvent.International journal of molecular sciences · 2020Article
- Natural Deep Eutectic Solvent as Extraction Media for the Main Phenolic Compounds from Olive Oil Processing Wastes.Antioxidants (Basel, Switzerland) · 2020Article
- Deep Eutectic Solvents as Effective Reaction Media for the Synthesis of 2-Hydroxyphenylbenzimidazole-based Scaffolds en Route to Donepezil-Like Compounds.Molecules (Basel, Switzerland) · 2020Article
- Sustainable and Selective Extraction of Lipids and Bioactive Compounds from Microalgae.Molecules (Basel, Switzerland) · 2019Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The exploitation and use of alternative synthetic methods, in the face of classical procedures that do not conform to the ethics of green chemistry, represent an ever-present problem in the pharmaceutical industry. The procedures for the synthesis of benzimidazoles have become a focus in synthetic organic chemistry, as they are building blocks of strong interest for the development of compounds with pharmacological activity. Various benzimidazole derivatives exhibit important activities such as antimicrobial, antiviral, anti-inflammatory, and analgesic activities, and some of the already synthesized compounds have found very strong applications in medicine praxis. Here we report a selective and sustainable method for the synthesis of 1,2-disubstituted or 2-substituted benzimidazoles, starting from
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.