Evidence map›Paper›PMID 31398853›Full record

ArticleJournal of clinical medicine2019

Pavlovian-To-Instrumental Transfer and Alcohol Consumption in Young Male Social Drinkers: Behavioral, Neural and Polygenic Correlates.

Maria Garbusow, Stephan Nebe, Christian Sommer, Sören Kuitunen-Paul, Miriam Sebold, Daniel J Schad, Eva Friedel, Ilya M Veer, Hans-Ulrich Wittchen, Michael A Rapp and 6 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 35 citations in OpenAlex.

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  11. Association of theJournal of psychopharmacology (Oxford, England) · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 9 institutions in 4 countries.

Maria GarbusowDepartment of Psychiatry and Psychotherapy, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany. maria.garbusow@charite.de.
Stephan NebeDepartment of Psychiatry and Psychotherapy, Technische Universität Dresden, 01187 Dresden, Germany.ORCID 0000-0003-3968-9557
Christian SommerDepartment of Psychiatry and Psychotherapy, Technische Universität Dresden, 01187 Dresden, Germany.
Sören Kuitunen-PaulInstitute of Clinical Psychology and Psychotherapy, Technische Universität Dresden, 01187 Dresden, Germany.
Miriam SeboldDepartment of Psychiatry and Psychotherapy, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.ORCID 0000-0002-6006-3201
Daniel J SchadDepartment of Psychiatry and Psychotherapy, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.
Eva FriedelDepartment of Psychiatry and Psychotherapy, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.
Ilya M VeerDepartment of Psychiatry and Psychotherapy, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.
Hans-Ulrich WittchenInstitute of Clinical Psychology and Psychotherapy, Technische Universität Dresden, 01187 Dresden, Germany.
Michael A RappSocial and Preventive Medicine, Area of Excellence Cognitive Sciences, University of Potsdam, 14469 Potsdam, Germany.
Stephan RipkeDepartment of Psychiatry and Psychotherapy, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.ORCID 0000-0003-3622-835X
Henrik WalterDepartment of Psychiatry and Psychotherapy, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.
Quentin J M HuysDivision of Psychiatry and Max Planck UCL Centre for Computational Psychiatry and Ageing Research, University College London, London WC1E 6BT, UK.
Florian SchlagenhaufDepartment of Psychiatry and Psychotherapy, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.
Michael N SmolkaDepartment of Psychiatry and Psychotherapy, Technische Universität Dresden, 01187 Dresden, Germany.
Andreas HeinzDepartment of Psychiatry and Psychotherapy, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.
Charité - Universitätsmedizin Berlin · DETechnische Universität Dresden · DEUniversity of Potsdam · DEBerlin Institute of Health at Charité - Universitätsmedizin Berlin · DEBroad Institute · USMax Planck Institute for Human Cognitive and Brain Sciences · DEUniversity College London · GBUniversity Hospital Carl Gustav Carus · DEUniversity of Zurich · CH

Funding

Deutsche Forschungsgemeinschaft DFG FOR 1617
6 · The paper itself

Abstract

In animals and humans, behavior can be influenced by irrelevant stimuli, a phenomenon called Pavlovian-to-instrumental transfer (PIT). In subjects with substance use disorder, PIT is even enhanced with functional activation in the nucleus accumbens (NAcc) and amygdala. While we observed enhanced behavioral and neural PIT effects in alcohol-dependent subjects, we here aimed to determine whether behavioral PIT is enhanced in young men with high-risk compared to low-risk drinking and subsequently related functional activation in an a-priori region of interest encompassing the NAcc and amygdala and related to polygenic risk for alcohol consumption. A representative sample of 18-year old men (

Indexed as

alcoholamygdalahigh risk drinkersPavlovian-to-instrumental transferpolygenic risk

Identifiers

PMID31398853
PMCPMC6723486
OpenAlexW2968100720

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.