Evidence map›Paper›PMID 31398817›Full record

ArticleInternational journal of environmental research and public health2019

Association of Environmental Features and the Risk of Alzheimer's Dementia in Older Adults: A Nationwide Longitudinal Case-Control Study.

Chih-Ching Liu, Chung-Yi Li, Shiann-Far Kung, Hsien-Wen Kuo, Nuan-Ching Huang, Yu Sun, Susan C Hu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of environmental research and public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 5 pooled it
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 5 syntheses or guidelines pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  4. Pooled it
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  6. Article
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  8. Review
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  10. Article
  11. Operationalizing Social Environments in Cognitive Aging and Dementia Research: A Scoping Review.International journal of environmental research and public health · 2021
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Chih-Ching LiuDepartment of Public Health, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan.
Chung-Yi LiDepartment of Public Health, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan.ORCID 0000-0002-0321-8908
Shiann-Far KungDepartment of Urban Planning, National Cheng Kung University, Tainan 701, Taiwan.
Hsien-Wen KuoInstitute of Environmental and Occupational Health Sciences, National Yang-Ming University, Taipei 112, Taiwan.ORCID 0000-0003-4184-4333
Nuan-Ching HuangHealthy Cities Research Center, Research and Services Headquarters, National Cheng Kung University, Tainan 701, Taiwan.
Yu SunDepartment of Neurology, En Chu Kong Hospital, New Taipei City 23702, Taiwan. sunyu.jj.lu@gmail.com.
Susan C HuDepartment of Public Health, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan. shuhu@mail.ncku.edu.tw.ORCID 0000-0003-2437-5918
National Cheng Kung University · TWChina Medical University · TWEn Chu Kong Hospital · TWNational Yang Ming Chiao Tung University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Little is known about the association between environmental features and the risk of Alzheimer's dementia (AD). This study aims to investigate the association of physical and social environments with the incidence of AD. We identified 12,401 newly diagnosed AD cases aged ≥65 years in 2010, with the same no. of matched controls from National Health Insurance claims in Taiwan. Environmental data were collected from government statistics including three physical environments and three social environments. Multilevel logistic regression was conducted to calculate the odds ratios (OR) of AD in association with environmental features at the township level. Results showed that living in the areas with higher availability of playgrounds and sport venues was associated with a 3% decreased odds of AD (95% CI = 0.96-0.99), while higher density of elderly living alone was associated with a 5% increased odds of AD (95% CI = 1.01-1.11), after controlling for individual and other environmental factors. In further examination by urbanization level, the above relationships were found only in rural areas but not in urban areas. This study provides evidence that specific physical and social environmental features have different impacts on the risk of AD.

Indexed as

Social EnvironmentAgedAged, 80 and overAlzheimer DiseaseCase-Control StudiesEnvironment DesignFemaleHumansIncidenceLogistic ModelsLongitudinal StudiesMaleOdds RatioRisk FactorsTaiwanAlzheimer’s dementiacase-control studyincidencelongitudinal studyphysical environmentssocial environments

Identifiers

PMID31398817
PMCPMC6721060
OpenAlexW2967977195

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.