SynthesisJournal of affective disorders2019
The association between cardiorespiratory fitness and the incidence of common mental health disorders: A systematic review and meta-analysis.
Synthesis in Journal of affective disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
89 citing papers in PubMed, 6 syntheses or guidelines pooled it, 166 citations in OpenAlex.
- Exercise interventions are most consistently supported for depressive disorders: an umbrella review of diagnosed depressive and anxiety disorders.Frontiers in psychiatry · 2026Pooled it
- Cardiorespiratory fitness and health in children and adolescents: an overview of systematic reviews with meta-analyses representing over 125 000 observations covering 33 health-related outcomes.British journal of sports medicine · 2025Pooled it
- Effects of plyometric training on health-related physical fitness in untrained participants: a systematic review and meta-analysis.Scientific reports · 2024Pooled it
- Cardiorespiratory fitness is a strong and consistent predictor of morbidity and mortality among adults: an overview of meta-analyses representing over 20.9 million observations from 199 unique cohort studies.British journal of sports medicine · 2024Pooled it
- Effects of high-intensity interval training on depressive and anxiety symptoms in healthy individuals: A systematic review and meta-analysis of randomized clinical trials.Scandinavian journal of medicine & science in sports · 2024Pooled it
- Healthier Minds in Fitter Bodies: A Systematic Review and Meta-Analysis of the Association between Physical Fitness and Mental Health in Youth.Sports medicine (Auckland, N.Z.) · 2021Pooled it
- Aerobic exercise impacts the anterior cingulate cortex in adolescents with subthreshold mood syndromes: a randomized controlled trial study.Translational psychiatry · 2020Trial
- Increased oxygen demand during exercise as a stimulus for neuroprotection: A working hypothesis.Neural regeneration research · 2026Article
- Physical Fitness and Device-Based Moderate-to-Vigorous Physical Activity and Risk of Long-Term Sickness Absence-A Prospective Cohort Study With 8-Year Follow-Up.European journal of sport science · 2026Article
- Longitudinal changes in cardiorespiratory fitness and risk of depressive and anxiety disorders in a nationwide cohort of 7 million participants.Scientific reports · 2026Article
- Associations of cardiorespiratory fitness and muscular fitness with plasma levels of endocannabinoids and their analogues in adults with diagnosed depression: SONRIE study.European archives of psychiatry and clinical neuroscience · 2026Article
- Moderate Vigorous Physical Activity for Mental Health in Sedentary Middle-Aged Adults.International journal of exercise science · 2026Article
- Association of physical fitness and overweight with mental and behavioural diagnoses in a population-based cohort of 156 202 young men.BMJ open sport & exercise medicine · 2026Article
- Estimated Cardiorespiratory Fitness and Grip Strength: Independent and Combined Associations With Multimorbidity Risk and Patterns in a Large-Scale Prospective Cohort Study.Journal of the American Heart Association · 2025Article
- Impaired cardiorespiratory fitness in psoriatic arthritis: insights from cardiopulmonary exercise testing.RMD open · 2025Article
- Overstated association between adolescent physical fitness and adulthood depression risk due to familial factors.Journal of internal medicine · 2025Article
- Physical exercise and depression in university students with psychological resilience as mediator and family support as moderator.Scientific reports · 2025Article
- Body Composition, Fitness, and Mental Health in Preadolescent Children.JAMA network open · 2025Article
- Associations between physical fitness and different aspects of screen time in children and adolescents.Scientific reports · 2025Article
- The relation between passively collected data and PTSD: a systematic review and meta-analysis.NPJ digital medicine · 2025Article
29 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundPhysical activity is associated with a lower incidence of common mental health disorder, but less is known about the impact of cardiorespiratory fitness (CRF).
methodsIn this review, we systematically evaluated the relationship between CRF and the incidence of common mental health disorders in prospective cohort studies. We systematically searched six major electronic databases from inception to 23rd of May 2019. We assessed study quality using the Newcastle-Ottawa scale.
resultsWe were able to pool the hazard ratios (HRs) and 95% confidence intervals (CIs) of four studies including at least 27,733,154 person-years of data. We found that low CRF (HR = 1.47, [95% CI 1.23 - 1.76] p < 0.001 I LIMITATIONS: We were only able to identify a small number of eligible studies from our search and heterogeneity was substantial in the subsequent meta-analysis.
conclusionsOur findings indicate that there is a longitudinal association between CRF levels and the risk of a common mental health disorder. CRF levels could be useful for identifying and preventing common mental health disorders at a population-level.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.