Evidence map›Paper›PMID 31397840›Full record

GuidelineEuropean heart journal. Cardiovascular pharmacotherapy2020

Lipid management in rheumatoid arthritis: a position paper of the Working Group on Cardiovascular Pharmacotherapy of the European Society of Cardiology.

Ivana Hollan, Nicoletta Ronda, Patrick Dessein, Stefan Agewall, George Karpouzas, Juan Tamargo, Alexander Niessner, Gianluigi Savarese, Giuseppe Rosano, Juan Carlos Kaski and 2 more

Open access · bronzeAbstract readPractice GuidelineReview
In one paragraph

Guideline in European heart journal. Cardiovascular pharmacotherapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 41 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Trial
  5. [Risk factors of carotid atherosclerosis in patients with rheumatoid arthritis].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2026
    Article
  6. Review
  7. Article
  8. Article
  9. Residual Traditional Risk in Non-Traditional Atherosclerotic Diseases.International journal of molecular sciences · 2025
    Review
  10. Article
  11. [Correlation between dyslipidemia and rheumatoid arthritis associated interstitial lung disease].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2023
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 10 institutions in 9 countries.

Ivana HollanLillehammer Hospital for Rheumatic Diseases, M. Grundtvigs veg 6, 2609 Lillehammer, Norway.
Nicoletta RondaParco Area delle Scienze 27/A, 43124 Parma, Italy.
Patrick DesseinCardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, 7 York Road, Parktown, Johannesburg 2193, South Africa.
Stefan AgewallDepartment of Cardiology, Oslo University Hospital Ullevål, Kirkeveien 166, 0450 Oslo, Norway.
George KarpouzasDepartment of Medicine, Division of Rheumatology, Los Angeles Biomedical Research Institute, Harbor-UCLA Medical Center, 1124 W Carson Street, Building E4-R17A,Torrance, CA 90502, USA.
Juan TamargoDepartment of Pharmacology and Toxicology, School of Medicine, Universidad Complutense, CIBERCV, Plaza de Ramón y Cajal s/n, 28040, Madrid, Spain.
Alexander NiessnerDivision of Cardiology, Department of Internal Medicine II, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria.
Gianluigi SavareseNorrbacka, S1:02, Karolinska University Hospital, 171 76 Stockholm, Sweden.
Giuseppe RosanoDepartment of Medical Sciences, IRCCS San Raffaele Roma, Via della Pisana 249, 00163 Roma, Italy.
Juan Carlos KaskiMolecular and Clinical Sciences Research Institute, St. George's, University of London, Cranmer Terrace, London SW17 ORE, UK.
Sven WassmannCardiology Pasing, Institutstr. 14, 81241 Munich, Germany.
Pier Luigi MeroniImmunorheumatology Research Laboratory, Istituto Auxologico Italiano, Via Ariosto, 14, 20145 Milan, Italy.
IRCCS Istituto Auxologico Italiano · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITKarolinska University Hospital · SELungenheilkunde München-Pasing · DEMedical University of Vienna · ATOslo University Hospital · NOSt George's, University of London · GBThe Lundquist Institute · USUniversidad Complutense de Madrid · ESUniversity of the Witwatersrand · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rheumatoid arthritis (RA) is associated with increased cardiovascular morbidity, partly due to alterations in lipoprotein quantity, quality and cell cholesterol trafficking. Although cardiovascular disease significantly contributes to mortality excess in RA, cardiovascular prevention has been largely insufficient. Because of limited evidence, optimal strategies for lipid management (LM) in RA have not been determined yet, and recommendations are largely based on expert opinions. In this position paper, we describe abnormalities in lipid metabolism and introduce a new algorithm for estimation of cardiovascular risk (CVR) and LM in RA. The algorithm stratifies patients according to RA-related factors impacting CVR (such as RA activity and severity and medication). We propose strategies for monitoring of lipid parameters and treatment of dyslipidaemia in RA (including lifestyle, statins and other lipid-modifying therapies, and disease modifying antirheumatic drugs). These opinion-based recommendations are meant to facilitate LM in RA until more evidence is available.

Indexed as

AlgorithmsAntirheumatic AgentsArthritis, RheumatoidBiomarkersCardiovascular DiseasesClinical Decision-MakingClinical Decision RulesDyslipidemiasHumansHypolipidemic AgentsLipidsRisk AssessmentRisk FactorsRisk Reduction BehaviorTreatment OutcomeAntirheumatic AgentsBiomarkersHypolipidemic AgentsLipidsAtherosclerosisCardiovascular riskInflammationLipid managementRheumatoid arthritisStatins

Identifiers

PMID31397840
PMCPMC13588645
OpenAlexW2967086772

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.