Evidence map›Paper›PMID 31397801›Full record

ArticleTransplantation2019

Unexpected Race and Ethnicity Differences in the US National Veterans Affairs Kidney Transplant Program.

Larissa Myaskovsky, Kellee Kendall, Xingyuan Li, Chung-Chou H Chang, John R Pleis, Emilee Croswell, C Graham Ford, Galen E Switzer, Anthony Langone, Anuja Mittal-Henkle and 5 more

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Transplantation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

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  4. Protocol for the IMPACT Trial: Improving Healthcare Outcomes in American Transplant Recipients Using Culturally-Tailored Novel Technology.Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 1 country.

Larissa MyaskovskyThe Center for Healthcare Equity in Kidney Disease (CHEK-D) and the Department of Internal Medicine, University of New Mexico, School of Medicine, Albuquerque, NM.
Kellee KendallDepartment of Medicine, University of Pittsburgh, School of Medicine, Pittsburgh, PA.
Xingyuan LiDepartment of Biostatistics, University of Pittsburgh, Pittsburgh, PA.
Chung-Chou H ChangDepartment of Medicine, University of Pittsburgh, School of Medicine, Pittsburgh, PA.
John R PleisDivision of Research and Methodology, National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, MD.
Emilee CroswellDepartment of Medicine, University of Pittsburgh, School of Medicine, Pittsburgh, PA.
C Graham FordThe Center for Healthcare Equity in Kidney Disease (CHEK-D) and the Department of Internal Medicine, University of New Mexico, School of Medicine, Albuquerque, NM.
Galen E SwitzerDepartment of Medicine, University of Pittsburgh, School of Medicine, Pittsburgh, PA.
Anthony LangoneRenal Section, Tennessee Valley VA Healthcare System, Nashville, TN.
Anuja Mittal-HenkleKaiser Permanente, Northwest, Portland, OR.
Somnath SahaCenter to Improve Veteran Involvement in Care (CIVIC), VA Portland Health Care System, Portland, OR.
Christie P ThomasRenal Section, Iowa City VA Healthcare System, Iowa City, IA.
Jareen Adams FlohrRenal Section, VA Pittsburgh Healthcare System, Pittsburgh, PA.
Mohan RamkumarDepartment of Medicine, University of Pittsburgh, School of Medicine, Pittsburgh, PA.
Mary Amanda DewDepartment of Psychiatry, Psychology, and Epidemiology University of Pittsburgh, Pittsburgh, PA.
University of Pittsburgh · USVA Pittsburgh Healthcare System · USKaiser Permanente · USUniversity of Iowa · USVanderbilt University · USVA Portland Health Care System · US

Funding

Increasing Equity in Transplant Evaluation and Living Donor Kidney TransplantationR01DK101715 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DEW, MARY AMANDA · 2014 to 2018
$2.7M
Understanding Race and Culture in Living Donor Kidney TransplantationR01DK081325 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MYASKOVSKY, LARISSA · 2009 to 2013
$1.4M
NIDDK NIH HHS R01 DK081325NIDDK NIH HHS R01 DK101715
6 · The paper itself

Abstract

backgroundRacial/ethnic minorities have lower rates of deceased kidney transplantation (DDKT) and living donor kidney transplantation (LDKT) in the United States. We examined whether social determinants of health (eg, demographics, cultural, psychosocial, knowledge factors) could account for differences in the Veterans Affairs (VA) Kidney Transplantation (KT) Program.

methodsWe conducted a multicenter longitudinal cohort study of 611 Veterans undergoing evaluation for KT at all National VA KT Centers (2010-2012) using an interview after KT evaluation and tracking participants via medical records through 2017.

resultsHispanics were more likely to get any KT (subdistribution hazard ratios [SHR] [95% confidence interval (CI)]: 1.8 [1.2-2.8]) or DDKT (SHR [95% CI]: 2.0 [1.3-3.2]) than non-Hispanic white in univariable analysis. Social determinants of health, including marital status (SHR [95% CI]: 0.6 [0.4-0.9]), religious objection to LDKT (SHR [95% CI]: 0.6 [0.4-1.0]), and donor preference (SHR [95% CI]: 2.5 [1.2-5.1]), accounted for some racial differences, and changes to Kidney Allocation System policy (SHR [95% CI]: 0.3 [0.2-0.5]) mitigated race differences in DDKT in multivariable analysis. For LDKT, non-Hispanic African American Veterans were less likely to receive an LDKT than non-Hispanic white (SHR [95% CI]: 0.2 [0.0-0.7]), but accounting for age (SHR [95% CI]: 1.0 [0.9-1.0]), insurance (SHR [95% CI]: 5.9 [1.1-33.7]), presenting with a living donor (SHR [95% CI]: 4.1 [1.4-12.3]), dialysis duration (SHR [95% CI]: 0.3 [0.2-0.6]), network of potential donors (SHR [95% CI]: 1.0 [1.0-1.1]), self-esteem (SHR [95% CI]: 0.4 [0.2-0.8]), transplant knowledge (SHR [95% CI]: 1.3 [1.0-1.7]), and changes to Kidney Allocation System policy (SHR [95% CI]: 10.3 [2.5-42.1]) in multivariable analysis eliminated those disparities.

conclusionsThe VA KT Program does not exhibit the same pattern of disparities in KT receipt as non-VA centers. Transplant centers can use identified risk factors to target patients who may need more support to ensure they receive a transplant.

Indexed as

EthnicityRacial GroupsFemaleFollow-Up StudiesHumansKidney Failure, ChronicKidney TransplantationMaleMiddle AgedMorbidityRetrospective StudiesRisk FactorsSurvival RateUnited StatesUnited States Department of Veterans AffairsVeterans

Identifiers

PMID31397801
PMCPMC6937592
OpenAlexW2969170277

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.