SynthesisJournal of cardiopulmonary rehabilitation and prevention2019
Exercise Interventions in Patients With Implantable Cardioverter-Defibrillators and Cardiac Resynchronization Therapy: A SYSTEMATIC REVIEW AND META-ANALYSIS.
Synthesis in Journal of cardiopulmonary rehabilitation and prevention, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed.
- Empowering congenital heart disease treatment: Physical activity prescription. The Italian proposal.International journal of cardiology. Congenital heart disease · 2026Article
- Effect of high-intensity interval training on peak oxygen uptake, quality of life, and ventricular arrhythmias in patients with an implantable cardioverter defibrillator: a randomized controlled trial.European heart journal open · 2026Article
- Sexual health in patients with an implantable cardioverter-defibrillator: A narrative review.Heart rhythm O2 · 2026Review
- Cardiac Rehabilitation in Patients with Implantable Cardioverter-Defibrillators: A Systematic Review and Meta-Analysis of Randomized Controlled Trials and TSA.Biomedicines · 2026Review
- How to Evaluate and Adjust the Recommended Level of Physical Activity in Patients with Congenital Heart Diseases? A Practical Approach.Journal of clinical medicine · 2025Review
- Cardiac Rehabilitation in the Era of CRT and ARNI: A Missing Link in Heart Failure with Reduced Ejection Fraction Care.Journal of clinical medicine · 2025Review
- Wearable Devices for Exercise Prescription and Physical Activity Monitoring in Patients with Various Cardiovascular Conditions.CJC open · 2025Review
- Relationship between activity and sleep, as measured through a wearable accelerometer, and appropriate cardioverter defibrillator interventions: a prospective SafeHeart substudy.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024Article
- JCS/JHRS 2022 Guideline on Diagnosis and Risk Assessment of Arrhythmia.Journal of arrhythmia · 2024Article
- Fine grained automatic left ventricle segmentation via ROI based Tri-Convolutional neural networks.Technology and health care : official journal of the European Society for Engineering and Medicine · 2024Article
- Protocol of randomized controlled trial to evaluate the effect of moderate exercise training on the functional capacity of patients with an implantable cardioverter defibrillator in a tertiary care center in South India.Journal of education and health promotion · 2024Article
- A survey of the implementation rate of cardiac rehabilitation for patients with heart disease undergoing device implantation in Japan.Journal of arrhythmia · 2022Article
- Efficacy and Safety of a Combined Aerobic, Strength and Flexibility Exercise Training Program in Patients with Implantable Cardiac Devices.Journal of cardiovascular development and disease · 2022Article
- Accelerometer-assessed physical behavior and the association with clinical outcomes in implantable cardioverter-defibrillator recipients: A systematic review.Cardiovascular digital health journal · 2022Review
- Cardiac Rehabilitation in German Speaking Countries of Europe-Evidence-Based Guidelines from Germany, Austria and Switzerland LLKardReha-DACH-Part 2.Journal of clinical medicine · 2021Review
- Impact of the COVID-19 lockdown on the arrhythmic burden of patients with implantable cardioverter-defibrillators.Pacing and clinical electrophysiology : PACE · 2021Article
- Aerobic exercise prescription in heart failure patients with cardiac resynchronization therapy.Journal of arrhythmia · 2021Review
- The Future of Exercise-Based Cardiac Rehabilitation for Patients With Heart Failure.Frontiers in cardiovascular medicine · 2021Review
- Impact of COVID-19 Pandemic on Physical Activity in Patients With Implantable Cardioverter-Defibrillators.Journal of cardiopulmonary rehabilitation and prevention · 2020Article
- [Research progress on cardiac rehabilitation in patients with implanted cardiac defibrillator].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2020Review
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
purposePhysical activity improves outcomes across a broad spectrum of cardiovascular disease. The safety and effectiveness of exercise-based interventions in patients with implantable cardioverter-defibrillators (ICDs) including cardiac resynchronization therapy defibrillators (CRT-Ds) remain poorly understood.
methodsWe identified clinical studies using the following search terms: "implantable cardioverter-defibrillators"; "ICD"; "cardiac resynchronization therapy"; "CRT"; and any one of the following: "activity"; "exercise"; "training"; or "rehabilitation"; from January 1, 2000 to October 1, 2015. Eligible studies were evaluated for design and clinical endpoints.
resultsA total of 16 studies were included: 8 randomized controlled trials, 5 single-arm trials, 2 observational cohort trials, and 1 randomized crossover trial. A total of 2547 patients were included (intervention groups = 1215 patients, control groups = 1332 patients). Exercise interventions varied widely in character, duration (median 84 d, range: 23-168 d), and follow-up time (median 109 d, range: 23 d to 48 mo). Exercise performance measures were the most common primary endpoints (87.5%), with most studies (81%) demonstrating significant improvement. Implantable cardioverter-defibrillator shocks were uncommon during active exercise intervention, with 6 shocks in 635 patients (0.9%). Implantable cardioverter-defibrillator shocks in follow-up were less common in patients receiving any exercise intervention (15.6% vs 23%, OR = 0.68; 95% CI, 0.48-0.80, P < .001). (Equation is included in full-text article.)O2 peak improved significantly in patients receiving exercise intervention (1.98 vs 0.36 mL/kg/min, P < .001).
conclusionIn conclusion, exercise interventions in patients with ICDs and CRT-Ds appear safe and effective. Lack of consensus on design and endpoints remains a barrier to broader application to this important patient population.
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