Evidence map›Paper›PMID 31397720›Full record

ArticleAIDS (London, England)2019

Resilience and psychosocial outcomes among South African adolescents affected by HIV.

Caroline Kuo, Ashleigh LoVette, Jennifer Pellowski, Abigail Harrison, Catherine Mathews, Don Operario, William Beardslee, Dan J Stein, Larry Brown

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in AIDS (London, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02432352 (Our Family Our Future), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02432352 phase1completednot on this map

Our Family Our Future: Family Prevention of HIV Risk and Depression in HIV-endemic South Africa

TypeinterventionalSponsorBrown UniversityRan2015 to 2017Enrolled146ConditionsSexual Behavior, DepressionArmsOur Family Our Future
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Caroline KuoDepartment of Behavioral and Social Sciences, Brown University School of Public Health.
Ashleigh LoVetteDepartment of Behavioral and Social Sciences, Brown University School of Public Health.
Jennifer PellowskiDepartment of Behavioral and Social Sciences, Brown University School of Public Health.
Abigail HarrisonDepartment of Behavioral and Social Sciences, Brown University School of Public Health.
Catherine MathewsHealth Systems Research Unit, South African Medical Research Council, Cape Town, South Africa.
Don OperarioDepartment of Behavioral and Social Sciences, Brown University School of Public Health.
William BeardsleeBoston Children's Hospital.
Dan J SteinSouth African MRC Unit on Risk and Resilience in Mental Disorders.
Larry BrownDepartment of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA.
John Brown University · USBrown University · USHarvard University · USSouth African Medical Research Council · ZAUniversity of Cape Town · ZA

Funding

Science/Technical CoreP2CHD041020 · NICHD · BROWN UNIVERSITY · PI ZHENCHAO QIAN · 2016 to 2026
$7.6M
Advancing the Culture of PhD Learning & Scholarship in Biology & Health SciencesR25GM083270 · NIGMS · BROWN UNIVERSITY · PI CAMPBELL, ANDREW G., HARRINGTON, ELIZABETH O · 2008 to 2021
$7.5M
Training in Child/Adolescent Biobehavioral HIV ResearchT32MH078788 · NIMH · RHODE ISLAND HOSPITAL · PI LARRY K BROWN · 2007 to 2026
$6.2M
Minority Populations Prevention Researcher TrainingR25HD045810 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI NEILANDS, TORSTEN BRIAN · 2003 to 2018
$4.3M
Partnerships for the Next Generation of HIV Social Science in South AfricaR24HD077976 · NICHD · BROWN UNIVERSITY · PI COLVIN, CHRISTOPHER JAMES, LURIE, MARK NATHAN · 2013 to 2017
$1.9M
Family Prevention of HIV Risk and Depression in HIV-endemic South AfricaK01MH096646 · NIMH · BROWN UNIVERSITY · PI KUO, CAROLINE CHIA · 2012 to 2016
$871k
NICHD NIH HHS P2C HD041020NICHD NIH HHS R24 HD077976NICHD NIH HHS R25 HD045810NIGMS NIH HHS R25 GM083270NIMH NIH HHS K01 MH096646NIMH NIH HHS L30 MH098313NIMH NIH HHS T32 MH078788
6 · The paper itself

Abstract

objectiveIn South Africa, adolescents account for the largest share of new HIV infections. Given the scale of the epidemic, millions of adolescents cope with familial HIV illness and AIDS orphanhood. Developing an understanding of adolescent resilience is vital for informing HIV and mental health prevention efforts.

designA cross-sectional survey of N = 195 South African adolescents, 13-15 years, and living in communities with high prevalence of HIV and poor mental health, was used to gather data on resilience, psychosocial factors, and mental health.

methodsParticipants were recruited through systematic community-based household sampling. Analysis was conducted on a subsample of adolescents identified as potentially vulnerable (n = 82); potential vulnerability was defined as adolescents living with HIV, residing with parents or caregivers living with HIV, or experiencing orphanhood. Differences on behavioral and psychosocial outcomes in those with higher and lower resilience were evaluated using SPSS software.

resultsAmong adolescents identified as potentially vulnerable (n = 82), those with higher resilience scores reported significantly lower behavioral problems using the total difficulties Strength and Difficulties Questionnaire score (P < 0.01) with a mean score difference of 2.76 (standard error = 1.02). Multivariate linear regressions were conducted with total difficulties Strength and Difficulties Questionnaire score as the dependent variable. Higher resilience among vulnerable youth was significantly associated with fewer behavioral problems (β = -0.229, P < 0.05), even after adjusting for variables that could also contribute to poor behavioral outcomes.

conclusionResilience is related to the behavioral health of vulnerable HIV-affected adolescents. Resilience-focused interventions hold promise for improving the behavioral health of adolescents living in high HIV prevalence settings.

Indexed as

Adaptation, PsychologicalAdolescent HealthResilience, PsychologicalAdolescentAdolescent BehaviorCaregiversChild, OrphanedChild WelfareCross-Sectional StudiesFemaleHIV InfectionsHumansLinear ModelsMaleMental HealthMultivariate Analysis

Identifiers

PMID31397720
PMCPMC7012534
OpenAlexW2943930519

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.