Evidence map›Paper›PMID 31397716›Full record

ArticleCritical care medicine2019

One-Year Outcomes Following Tracheostomy for Acute Respiratory Failure.

Anuj B Mehta, Allan J Walkey, Douglas Curran-Everett, Ivor S Douglas

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Critical care medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04987398 (Analysis of Ventilation Weaning Strategies and Correlation to Outcomes in Tracheostomized Patients in the Intensive Care Unit of the Lausanne University Hospital), which is not on this map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04987398 completednot on this mapstarted 2021, after this paper: background citation

Analysis of Ventilation Weaning Strategies and Correlation to Outcomes in Tracheostomized Patients in the Intensive Care Unit of the Lausanne University Hospital

TypeobservationalSponsorPiquilloud Imboden LiseRan2021 to 2022Enrolled80ConditionsRespiratory Failure, Tracheostomy Complication
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Tracheostomy in critically ill patients with SARS 2 COVID-19 infection: a prospective observational multi-center study of short- and long-term outcomes.Canadian journal of respiratory therapy : CJRT = Revue canadienne de la therapie respiratoire : RCTR · 2022
    Article
  18. Article
  19. Article
  20. Observational
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Anuj B Mehta1Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, National Jewish Health, Denver, CO. 2Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado School of Medicine, Aurora, CO. 3The Pulmonary Center, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Boston University School of Medicine, Boston, MA. 4Evans Center for Implementation and Improvement Sciences, Department of Medicine, Boston University School of Medicine, Boston, MA. 5Division of Biostatistics, Department of Medicine, National Jewish Health, Denver, CO. 6Division of Pulmonary and Critical Care Medicine, Department of Medicine, Denver Health Hospital Association, Denver, CO.
Allan J WalkeyThe Pulmonary Center, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Boston University School of Medicine, Boston, MA.
Douglas Curran-EverettDivision of Biostatistics, Department of Medicine, National Jewish Health, Denver, CO.
Ivor S DouglasDivision of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado School of Medicine, Aurora, CO.
Boston University · USUniversity of Colorado Denver · US

Funding

Genetic Epidemiology of COPDU01HL089897 · NHLBI · NATIONAL JEWISH HEALTH · PI CRAPO, JAMES D · 2007 to 2021
$56.9M
Metabolomic signatures of empysema and COPD progression in the COPDGene cohortR01HL089897 · NHLBI · NATIONAL JEWISH HEALTH · PI CRAPO, JAMES D · 2012 to 2016
$31.1M
Prediction of Functional Outcomes from Chronic Critical IllnessR01NR016459 · NINR · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CARSON, SHANNON S, DOUGLAS, IVOR SAMUEL · 2016 to 2020
$3.4M
IMPlementation to Achieve Clinical Transformation (IMPACT): The Colorado Training ProgramK12HL137862 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI GLASGOW, RUSSELL E, HAVRANEK, EDWARD PAUL · 2017 to 2021
$2.9M
Automated detection and prediction of atrial fibrillation during sepsisR01HL136660 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI WALKEY, ALLAN J. · 2017 to 2020
$2.2M
Developing a Novel Decision Aid for Tracheostomy to Support Shared Decision-Making in the Intensive Care UnitK23HL141704 · NHLBI · NATIONAL JEWISH HEALTH · PI MEHTA, ANUJ · 2019 to 2023
$818k
NHLBI NIH HHS K12 HL137862NHLBI NIH HHS K23 HL141704NHLBI NIH HHS R01 HL089897NHLBI NIH HHS R01 HL136660NHLBI NIH HHS U01 HL089897NINR NIH HHS R01 NR016459
6 · The paper itself

Abstract

objectivesTracheostomy utilization has dramatically increased recently. Large gaps exist between expected and actual outcomes resulting in significant decisional conflict and regret. We determined 1-year patient outcomes and healthcare utilization following tracheostomy to aid in decision-making and resource allocation.

designRetrospective cohort study.

settingAll California hospital discharges from 2012 to 2013 with follow-up through 2014. PATIENTS: Nonsurgical patients who received a tracheostomy for acute respiratory failure.

interventionsNone. MEASUREMENTS AND MAIN

resultsOur primary outcome was 30-day, 90-day, and 1-year mortality. We also determined hospitals readmissions rates and healthcare utilization in the first year following tracheostomy. We identified 8,343 tracheostomies during the study period. One-year mortality following tracheostomy was high, 46.5%. Older adults (≥ 65 yr) had significantly higher mortality compared with younger patients (< 65 yr) (54.7% vs 36.5%; p < 0.0001). Median survival for older adults was 175 days (95% CI, 150-202 d) compared with greater than 1 year for younger adults (adjusted hazard ratio, 1.25; 95% CI, 1.14-1.36). Within 1 year of tracheostomy, 60.3% of patients required hospital readmission. Older adults were more likely to be readmitted in the first year after tracheostomy compared with younger adults (66.1% vs 55.2%; adjusted hazard ratio, 1.19; 95% CI, 1.09-1.29). Total short-term acute care hospital costs (index and readmissions) in the first year after tracheostomy were high (mean, $215,369; SD, $160,874).

conclusionsLong-term outcomes following tracheostomy are extremely poor with high mortality, morbidity, and healthcare resource utilization especially among older patients. Some subsets of younger patients may have better outcomes compared with the general tracheostomy population. Short-term acute care costs were extremely high in the first year following tracheostomy. If extended to the entire U.S. population, total short-term acute care hospital costs approach $11 billion dollars per year for tracheostomy-related to acute respiratory failure. These findings may aid families and surrogates in the decision-making process.

Indexed as

TracheostomyAgedAged, 80 and overAge FactorsCaliforniaCohort StudiesFemaleHeart FailureHospital CostsHumansLong-Term CareMaleMiddle AgedNeoplasmsPatient ReadmissionRenal Insufficiency, Chronic

Identifiers

PMID31397716
PMCPMC7262790
OpenAlexW2968202515

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.