ArticleInternational journal of methods in psychiatric research2019
Indicators of mental disorders in UK Biobank-A comparison of approaches.
Article in International journal of methods in psychiatric research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.
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Who cites it
59 citing papers in PubMed, 128 citations in OpenAlex.
- Pre-psychosis in later life as a risk factor for progressive cognitive decline: Findings from the IPA psychosis in neurodegenerative disease working group.International psychogeriatrics · 2026Review
- Adversity as the key feature: neuroimaging profiles of subtypes from multiple depression risk factors.Psychological medicine · 2026Article
- Cross-sectional and prospective associations between multidimensional psychological distress and urogenital disorders: findings from the UK biobank.Scientific reports · 2026Article
- Combinations of mental disorders and their association with mortality in the UK Biobank.BMC psychiatry · 2026Article
- Association between neuroticism, genetic susceptibility, and peripheral artery disease risk: a prospective study in UK Biobank.European archives of psychiatry and clinical neuroscience · 2026Article
- Mediators of the association between psychological distress and mortality in people diagnosed with cancer.Nature communications · 2025Article
- Mind the Gap: A Retrospective Study of Discrepancies in Self-Reported and Administrative Database-Identified Mental Health Issues in Slovenia.Zdravstveno varstvo · 2025Article
- Unlocking mental health insights with UK Biobank data: Past use and future opportunities.Psychological medicine · 2025Review
- Neurobiological correlates of schizophrenia-specific and highly pleiotropic genetic risk scores for neuropsychiatric disorders.Translational psychiatry · 2025Article
- Genome-wide interaction association analysis identifies interactive effects of childhood maltreatment and kynurenine pathway on depression.Nature communications · 2025Article
- Mapping the exposome of mental health: exposome-wide association study of mental health outcomes among UK Biobank participants.Psychological medicine · 2025Article
- Striatal dopamine gene network moderates the effect of early adversity on the risk for adult psychiatric and cardiometabolic comorbidity.Scientific reports · 2024Article
- Assessing the validity of a self-reported clinical diagnosis of schizophrenia.Schizophrenia (Heidelberg, Germany) · 2024Article
- Investigating the Relationship between Oral Health and Severe Mental Illness: Analysis of NHANES 1999-2016.Dentistry journal · 2024Article
- Heavy Lifetime Cannabis Use and Mortality by Sex.JAMA network open · 2024Article
- Transdiagnostic clustering and network analysis for questionnaire-based symptom profiling and drug recommendation in the UK Biobank and a Korean cohort.Scientific reports · 2024Article
- Peripheral vertigo and subsequent risk of depression and anxiety disorders: a prospective cohort study using the UK Biobank.BMC medicine · 2024Article
- Article
- Exploring the Interplay between Mitochondrial DNA and Lifestyle Factors in the Pathogenesis of Psychiatric Disorders.Depression and anxiety · 2024Article
- Dietary Inflammatory Potential, Inflammation-Related Lifestyle Factors, and Incident Anxiety Disorders: A Prospective Cohort Study.Nutrients · 2023Article
Corrections and comments
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Authors and funding
14 authors at 5 institutions in 1 country.
Funding
Abstract
objectivesFor many research cohorts, it is not practical to provide a "gold-standard" mental health diagnosis. It is therefore important for mental health research that potential alternative measures for ascertaining mental disorder status are understood.
methodsData from UK Biobank in those participants who had completed the online Mental Health Questionnaire (n = 157,363) were used to compare the classification of mental disorder by four methods: symptom-based outcome (self-complete based on diagnostic interviews), self-reported diagnosis, hospital data linkage, and self-report medication.
resultsParticipants self-reporting any psychiatric diagnosis had elevated risk of any symptom-based outcome. Cohen's κ between self-reported diagnosis and symptom-based outcome was 0.46 for depression, 0.28 for bipolar affective disorder, and 0.24 for anxiety. There were small numbers of participants uniquely identified by hospital data linkage and medication.
conclusionOur results confirm that ascertainment of mental disorder diagnosis in large cohorts such as UK Biobank is complex. There may not be one method of classification that is right for all circumstances, but an informed and transparent use of outcome measure(s) to suit each research question will maximise the potential of UK Biobank and other resources for mental health research.
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