Evidence map›Paper›PMID 31396919›Full record

ArticleInternal and emergency medicine2020

Direct-acting antivirals improve endothelial function in patients with chronic hepatitis: a prospective cohort study.

Matteo Nicola Dario Di Minno, Pasquale Ambrosino, Antonio Riccardo Buonomo, Biagio Pinchera, Ilenia Calcaterra, Manuel Crispo, Riccardo Scotto, Francesco Borgia, Consalvo Mattia, Ivan Gentile

Abstract read
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In one paragraph

Article in Internal and emergency medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Peripheral neuropathy after viral eradication with direct-acting antivirals in chronic HCV hepatitis: A prospective study.Liver international : official journal of the International Association for the Study of the Liver · 2021
    Article
  7. Review
  8. The effect of direct acting antiviral agents on vascular endothelial function in Egyptian patients with chronic hepatitis C virus infection.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2021
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Observational
  14. The impact of infection with hepatitis C virus on cardiovascular risk.American journal of cardiovascular disease · 2020
    Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Matteo Nicola Dario Di MinnoDepartment of Translational Medical Sciences, Federico II University, Via S. Pansini 5, 80131, Naples, Italy. dario.diminno@hotmail.it.ORCID 0000-0001-8059-3819
Pasquale AmbrosinoDepartment of Clinical Medicine and Surgery, Federico II University, Naples, Italy.
Antonio Riccardo BuonomoDepartment of Clinical Medicine and Surgery, Federico II University, Naples, Italy.
Biagio PincheraDepartment of Clinical Medicine and Surgery, Federico II University, Naples, Italy.
Ilenia CalcaterraDepartment of Clinical Medicine and Surgery, Federico II University, Naples, Italy.
Manuel CrispoDepartment of Clinical Medicine and Surgery, Federico II University, Naples, Italy.
Riccardo ScottoDepartment of Clinical Medicine and Surgery, Federico II University, Naples, Italy.
Francesco BorgiaDepartment of Advanced Biomedical Sciences, Federico II University, Naples, Italy.
Consalvo MattiaDepartment of Medical and Surgical Sciences and Biotechnologies, Unit of Anaesthesiology, Intensive Care Medicine and Pain Therapy, Faculty of Pharmacy and Medicine, "Polo Pontino", "Sapienza" University of Rome, Rome, Italy.
Ivan GentileDepartment of Clinical Medicine and Surgery, Federico II University, Naples, Italy.
Federico II University Hospital · ITSapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis C virus (HCV) infection is associated with increased cardiovascular risk. We evaluated effects of direct-acting antiviral agents (DAAs) on flow-mediated dilation (FMD), a recognized marker of cardiovascular risk. We evaluated FMD and post-ischemic hyperemia (PIH) in consecutive HCV out-patients before starting DAAs, at the end of treatment (T

Indexed as

AgedAntiviral AgentsCohort StudiesEndotheliumFemaleHepacivirusHepatitis CHepatitis, ChronicHumansItalyLiver CirrhosisMaleMiddle AgedProspective StudiesProtective FactorsAntiviral AgentsChronic hepatitis CDirect-acting antiviral agentsEndothelial function

Identifiers

PMID31396919
OpenAlexW2967643147

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.