Evidence map›Paper›PMID 31396838›Full record

ArticlePurinergic signalling2019

The P2-receptor-mediated Ca

Jan K Hennigs, Nicole Lüneburg, Annett Stage, Melanie Schmitz, Jakob Körbelin, Lars Harbaum, Christiane Matuszcak, Julia Mienert, Carsten Bokemeyer, Rainer H Böger and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Purinergic signalling, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. 4D force patterning enables spatial control of angiogenesis.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Single-cell RNA sequencing: new insights for pulmonary endothelial cells.Frontiers in cell and developmental biology · 2025
    Review
  4. Review
  5. Macrophage P2YActa pharmaceutica Sinica. B · 2024
    Article
  6. Review
  7. Review
  8. P2YFrontiers in immunology · 2023
    Article
  9. Review
  10. Effect ofNutrients · 2022
    Article
  11. Article
  12. Review
  13. Role of the Purinergic P2Y2 Receptor in Pulmonary Hypertension.International journal of environmental research and public health · 2021
    Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Purinergic Dysfunction in Pulmonary Arterial Hypertension.Journal of the American Heart Association · 2020
    Review
  19. P2 Purinergic Signaling in the Distal Lung in Health and Disease.International journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Jan K HennigsDepartment of Pneumology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany. j.hennigs@uke.de.ORCID 0000-0002-7784-8267
Nicole LüneburgInstitute of Clinical Pharmacology, Center of Experimental Medicine, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany.
Annett StageCenter for Pulmonary Arterial Hypertension Hamburg, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany.
Melanie SchmitzDepartment of Pneumology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany.
Jakob KörbelinDepartment of Pneumology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany.
Lars HarbaumDepartment of Pneumology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany.
Christiane MatuszcakDepartment of Pneumology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany.
Julia MienertDepartment of Pneumology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany.
Carsten BokemeyerII. Department of Internal Medicine, Center of Oncology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany.
Rainer H BögerInstitute of Clinical Pharmacology, Center of Experimental Medicine, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany.
Rainer KiefmannDepartment of Anesthesiology, Center of Anesthesiology and Critical Care Medicine, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany.
Hans KloseDepartment of Pneumology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany.
Universität Hamburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dysfunction of the pulmonary endothelium is associated with most lung diseases. Extracellular nucleotides modulate a plethora of endothelial functions in the lung such as vessel integrity, vasodilatation, inflammatory, and thrombotic responses as well as survival and DNA repair, mostly via Ca

Indexed as

Calcium SignalingCells, CulturedEndothelium, VascularHumansLungPulmonary Arterial HypertensionReceptors, Purinergic P2Receptors, Purinergic P2ATPCardiovascular diseaseCD39Endothelial dysfunctionLungProliferationPurinoceptorRemodelingUTP

Identifiers

PMID31396838
PMCPMC6737170
OpenAlexW2967006713

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.