Evidence map›Paper›PMID 31396739›Full record

Observational studyPediatric surgery international2019

Impact of congenital heart disease on outcomes after primary repair of esophageal atresia: a retrospective observational study using a nationwide database in Japan.

Tetsuya Ishimaru, Michimasa Fujiogi, Nobuaki Michihata, Hiroki Matsui, Kiyohide Fushimi, Hiroshi Kawashima, Jun Fujishiro, Hideo Yasunaga

Registry-linked trialAbstract readMulticenter StudyObservational Study
PubMed Publisher
In one paragraph

Observational study in Pediatric surgery international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07210736 (Evolution of Neonates With Esophageal Atresia in Brazil - A Multicenter Study), which is not on this map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07210736 not yet recruitingnot on this mapstarted 2025, after this paper: background citation

Evolution of Neonates With Esophageal Atresia in Brazil - A Multicenter Study

TypeobservationalSponsorUniversity of Sao Paulo General HospitalRan2025 to 2027Enrolled1,000ConditionsEsophageal Atresia
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Tetsuya IshimaruDepartment of Pediatric Surgery, Saitama Children's Medical Center, 1-2 Shintoshin, Chuo-ku, Saitama, 330-8777, Japan. i-tetsuya@umin.ac.jp.
Michimasa FujiogiDepartment of Pediatric Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Nobuaki MichihataDepartment of Health Services Research, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Hiroki MatsuiDepartment of Clinical Epidemiology and Health Economics, School of Public Health, The University of Tokyo, Tokyo, Japan.
Kiyohide FushimiDepartment of Health Policy and Informatics, Tokyo Medical and Dental University Graduate School, Tokyo, Japan.
Hiroshi KawashimaDepartment of Pediatric Surgery, Saitama Children's Medical Center, 1-2 Shintoshin, Chuo-ku, Saitama, 330-8777, Japan.
Jun FujishiroDepartment of Pediatric Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Hideo YasunagaDepartment of Clinical Epidemiology and Health Economics, School of Public Health, The University of Tokyo, Tokyo, Japan.
The University of Tokyo · JPSaitama Children's Medical Center · JPUniversity of Tokyo Health Sciences · JPTokyo Medical and Dental University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo verify the association between congenital heart disease (CHD) and postoperative complications after primary repair of esophageal atresia in patients from a Japanese nationwide database.

methodsWe identified babies in the Diagnosis Procedure Combination database who underwent radical surgery for esophageal atresia from 2010 to 2016. We used multivariable logistic regression analyses to evaluate the occurrence of anastomotic leakage and anastomotic stricture.

resultsAmong 431 patients who underwent primary anastomosis, 114 patients (27%) had CHD. Anastomotic leakage occurred in 77 patients (17.9%) and stricture in 154 (35.7%). Compared with patients whose anesthetic duration was less than 240 min, those with anesthesia lasting from 240 to 360 min (odds ratio 2.49; 95% confidence interval (CI) 1.17-5.27; p = 0.02) or more than 360 min (odds ratio 4.10; 95% CI 1.69-9.96; p = 0.002) were more likely to experience anastomotic leakage. Male patients had a lower risk of anastomotic stricture than female patients (odds ratio 0.65; 95% CI 0.43-0.9; p = 0.04).

conclusionsCHD was not associated with anastomotic leakage or stricture. The only significant predictor of anastomotic leakage was duration of anesthesia.

Indexed as

Abnormalities, MultipleAnastomosis, SurgicalAnastomotic LeakData ManagementEsophageal AtresiaFemaleHeart Defects, CongenitalHumansIncidenceInfant, NewbornJapanMalePostoperative ComplicationsRetrospective StudiesAnastomotic leakAnastomotic strictureComplicationsCongenital heart diseaseEsophageal atresia

Identifiers

PMID31396739
OpenAlexW2968410748

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.