Evidence map›Paper›PMID 31396722›Full record

ArticleJournal of medical systems2019

Automated Detection of Alzheimer's Disease Using Brain MRI Images- A Study with Various Feature Extraction Techniques.

U Rajendra Acharya, Steven Lawrence Fernandes, Joel En WeiKoh, Edward J Ciaccio, Mohd Kamil Mohd Fabell, U John Tanik, V Rajinikanth, Chai Hong Yeong

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Article in Journal of medical systems, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  20. Deep Learning-Based Diagnosis of Alzheimer's Disease.Journal of personalized medicine · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

U Rajendra AcharyaDepartment of Electronics and Computer Engineering, Ngee Ann Polytechnic, Singapore, Singapore.
Steven Lawrence FernandesDepartment of Electronics and Communication Engineering, Sahyadri College of Engineering & Management, Mangaluru, India.
Joel En WeiKohDepartment of Electronics and Computer Engineering, Ngee Ann Polytechnic, Singapore, Singapore.
Edward J CiaccioDepartment of Medicine, Columbia University, New York, NY, USA.
Mohd Kamil Mohd FabellDepartment of Biomedical Imaging, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
U John TanikDepartment of Computer Science and Information Systems, Texas A&M University-Commerce, Commerce, TX, USA.
V RajinikanthDepartment of Electronics and Instrumentation, St. Joseph's College of Engineering, Chennai, 600119, India. v.rajinikanth@ieee.org.ORCID http://orcid.org/0000-0003-3897-4460
Chai Hong YeongSchool of Medicine, Faculty of Health and Medical Sciences, Taylor's University, 47500, Subang Jaya, Malaysia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this work is to develop a Computer-Aided-Brain-Diagnosis (CABD) system that can determine if a brain scan shows signs of Alzheimer's disease. The method utilizes Magnetic Resonance Imaging (MRI) for classification with several feature extraction techniques. MRI is a non-invasive procedure, widely adopted in hospitals to examine cognitive abnormalities. Images are acquired using the T2 imaging sequence. The paradigm consists of a series of quantitative techniques: filtering, feature extraction, Student's t-test based feature selection, and k-Nearest Neighbor (KNN) based classification. Additionally, a comparative analysis is done by implementing other feature extraction procedures that are described in the literature. Our findings suggest that the Shearlet Transform (ST) feature extraction technique offers improved results for Alzheimer's diagnosis as compared to alternative methods. The proposed CABD tool with the ST + KNN technique provided accuracy of 94.54%, precision of 88.33%, sensitivity of 96.30% and specificity of 93.64%. Furthermore, this tool also offered an accuracy, precision, sensitivity and specificity of 98.48%, 100%, 96.97% and 100%, respectively, with the benchmark MRI database.

Indexed as

Alzheimer DiseaseBrainDiagnosis, Computer-AssistedHumansImage Interpretation, Computer-AssistedMagnetic Resonance ImagingPattern Recognition, AutomatedAlzheimer’s diseaseBrain MRIFeature extractionKNN classifierPerformance evaluation

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.