Evidence map›Paper›PMID 31396712›Full record

ArticleMikrochimica acta2019

Colorimetric detection of Staphylococcus aureus using gold nanorods labeled with yolk immunoglobulin and urease, magnetic beads, and a phenolphthalein impregnated test paper.

Bo Pang, Yan Zheng, Juan Wang, Yushen Liu, Xiuling Song, Jinhua Li, Shuo Yao, Kaiyue Fu, Kun Xu, Chao Zhao and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in Mikrochimica acta, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 35 citations in OpenAlex.

  1. Advances in methods for rapid detection of Staphylococcus aureus and methicillin-resistant S. aureus.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2025
    Review
  2. Article
  3. IgYs: on her majesty's secret service.Frontiers in immunology · 2023
    Review
  4. Paper-based sensors for bacteria detection.Nature reviews bioengineering · 2023
    Review
  5. Preparation of IgY Oriented Conjugated FeFrontiers in public health · 2022
    Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Bo PangSchool of Public Health, Jilin University, Changchun, 130021, People's Republic of China.
Yan ZhengDepartment of Geriatrics, the First Hospital of Jilin University, Changchun, 130021, People's Republic of China.
Juan WangSchool of Public Health, Jilin University, Changchun, 130021, People's Republic of China.
Yushen LiuSchool of Public Health, Jilin University, Changchun, 130021, People's Republic of China.
Xiuling SongSchool of Public Health, Jilin University, Changchun, 130021, People's Republic of China.
Jinhua LiSchool of Public Health, Jilin University, Changchun, 130021, People's Republic of China.
Shuo YaoSchool of Public Health, Jilin University, Changchun, 130021, People's Republic of China.
Kaiyue FuSchool of Public Health, Jilin University, Changchun, 130021, People's Republic of China.
Kun XuSchool of Public Health, Jilin University, Changchun, 130021, People's Republic of China. xukun@jlu.edu.cn.
Chao ZhaoSchool of Public Health, Jilin University, Changchun, 130021, People's Republic of China. czhao0529@jlu.edu.cn.
Juan LiSchool of Public Health, Jilin University, Changchun, 130021, People's Republic of China. li_juan@jlu.edu.cn.
Jilin University · CN

Funding

Department of Science and Technology of Jilin Province 20170204003SFJilin University 101832018C061National Natural Science Foundation of China 81473018National Natural Science Foundation of China 81872668
6 · The paper itself

Abstract

A colorimetric test is described for the rapid detection of Staphylococcus aureus (SA). Gold nanorods (AuNRs) are first labeled with urease and yolk immunoglobulin (IgY). This probe can specifically bind SA. In the next step, nonspecific magnetic beads and sample are added. This leads to the formation of the AuNR-IgY-SA-nMB immunocomplex which is then magnetically separated. Finally, a solution of urea is added to the supernatant. Ureases catalyzes the decomposition of urea which results in an increase in the pH value. The increase in the pH value is detected by using a phenolphthalein test paper which undergoes a color change from white to pink. The analytical process can be completed within 20 min. The method is highly specific and can detect as little as 476 cfu·mL

Indexed as

Biosensing TechniquesColorimetryEgg YolkGoldImmunoglobulinsMagnetsMicrospheresNanotubesPaperPhenolphthaleinStaphylococcus aureusUreaseGoldImmunoglobulinsPhenolphthaleinUreaseFood safetyImage analysisImmunocomplexMagnetic separationNanoparticlespH changeUreaVisual detection

Identifiers

PMID31396712
OpenAlexW2967729756

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.