Evidence map›Paper›PMID 31396568›Full record

ArticleCommunications biology2019

Cyclooxygenase inhibitors impair CD4 T cell immunity and exacerbate

Rasmus Mortensen, Helena Strand Clemmensen, Joshua S Woodworth, Marie Louise Therkelsen, Tehmina Mustafa, Kristian Tonby, Synne Jenum, Else Marie Agger, Anne Ma Dyrhol-Riise, Peter Andersen

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Communications biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 44 citations in OpenAlex.

  1. Trial
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  4. Article
  5. A CD4Immunity · 2025
    Article
  6. Article
  7. Host-directed therapy for tuberculosis.European journal of medical research · 2025
    Review
  8. MedComm · 2023
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Rasmus Mortensen1Department of Infectious Disease Immunology, Statens Serum Institut, 2300 Copenhagen S, Denmark.ORCID 0000-0003-0177-3032
Helena Strand Clemmensen1Department of Infectious Disease Immunology, Statens Serum Institut, 2300 Copenhagen S, Denmark.ORCID 0000-0002-2994-3120
Joshua S Woodworth1Department of Infectious Disease Immunology, Statens Serum Institut, 2300 Copenhagen S, Denmark.ORCID 0000-0002-0771-9056
Marie Louise Therkelsen1Department of Infectious Disease Immunology, Statens Serum Institut, 2300 Copenhagen S, Denmark.
Tehmina Mustafa2Centre for International Health, Department of Global Public Health and Primary Care, University of Bergen & Department of Thoracic Medicine, Haukeland University Hospital, 5021 Bergen, Norway.
Kristian Tonby3Department of Infectious Diseases, Oslo University Hospital, 0424 Oslo, Norway.
Synne Jenum3Department of Infectious Diseases, Oslo University Hospital, 0424 Oslo, Norway.
Else Marie Agger1Department of Infectious Disease Immunology, Statens Serum Institut, 2300 Copenhagen S, Denmark.
Anne Ma Dyrhol-Riise3Department of Infectious Diseases, Oslo University Hospital, 0424 Oslo, Norway.
Peter Andersen1Department of Infectious Disease Immunology, Statens Serum Institut, 2300 Copenhagen S, Denmark.
Statens Serum Institut · DKOslo University Hospital · NOHaukeland University Hospital · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tuberculosis, caused by infection with

Indexed as

Adoptive TransferAerosolsAnimalsBacterial LoadCelecoxibCell DifferentiationCyclooxygenase 2 InhibitorsCyclooxygenase InhibitorsDisease Models, AnimalDisease ProgressionFemaleHost-Pathogen InteractionsIbuprofenInhalation ExposureInterferon-gammaLungAerosolsCelecoxibCyclooxygenase 2 InhibitorsCyclooxygenase InhibitorsIbuprofenIFNG protein, humanInterferon-gammaBacteriaTuberculosis

Identifiers

PMID31396568
PMCPMC6683187
OpenAlexW2966536475

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.