Evidence map›Paper›PMID 31396560›Full record

ArticlePediatric dimensions2019

Toxic metals in cord blood and later development of Type 1 diabetes.

J Ludvigsson, P Andersson-White, C Guerrero-Bosagna

Open access · diamondAbstract read
In one paragraph

Article in Pediatric dimensions, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Evaluation of Fetal Exposures to Metals and Metalloids through Meconium Analyses: A Review.International journal of environmental research and public health · 2021
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Endocrine Disrupting Chemicals and Type 1 Diabetes.International journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

J LudvigssonDepartment of Clinical and Experimental Medicine, Division of Pediatrics, Linköping University, Linköping, Sweden.
P Andersson-WhiteCrown Princess Victoria Children's Hospital, Region Östergötland. Linköping Sweden.
C Guerrero-BosagnaIFM Biology, Linköping, University; Linköping university, Linköping, Sweden.
Linköping University · SECounty Administrative Board · SE

Funding

Trial to Reduce IDDM in the Genetically at Risk StudyU01HD040364 · NICHD · UNIVERSITY OF HELSINKI · PI KNIP, MIKAEL · 2001 to 2015
$32.7M
Early Dietary Intervention and Later Signs of Beta-Cell Autoimmunity: Potential MDP3DK094338 · NIDDK · UNIVERSITY OF HELSINKI · PI KNIP, MIKAEL · 2012 to 2012
$1.9M
NICHD NIH HHS U01 HD040364NIDDK NIH HHS DP3 DK094338
6 · The paper itself

Abstract

The incidence of type 1 diabetes (T1D) has increased explained by changes in environment or lifestyle. In modern society dissemination of heavy metals has increased. As the autoimmune process usually starts already, we hypothesized that exposure to toxic metals during fetal life might contribute to development of T1D in children. We analysed arsenic (AS), aluminium (Al), cadmium (Cd), lithium (Li), mercury (Hg), lead (Pb), in cord blood of 20 children who later developed T1D (probands), and in 40 age-and sex-matched controls. Analysis of heavy metals in cord blood was performed by ALS Scandinavia AB (Luleå, Sweden) using the 'ultrasensitive inductively coupled plasma sector field mass spectrometry method' (ICP-SFMS) after acid digestion with HNO

Indexed as

ABISaetiologychildrentoxic metalstype 1 diabetes

Identifiers

PMID31396560
PMCPMC6687082
OpenAlexW2964406762

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.