Evidence map›Paper›PMID 31396539›Full record

ArticleJournal of diabetes research2019

Polymorphisms in

Xiaoxiao Sun, Ying Xia, Yue Liu, Yanfei Wang, Shuoming Luo, Jian Lin, Gan Huang, Xia Li, Zhiguo Xie, Zhiguang Zhou

Open access · goldAbstract read
In one paragraph

Article in Journal of diabetes research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. NLRP inflammasomes in health and disease.Molecular biomedicine · 2024
    Review
  3. A common variant close to the "tripwire" linker region of NLRP1 contributes to severe COVID-19.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2023
    Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. rs3806265 and rs4612666 of theFrontiers in endocrinology · 2022
    Article
  12. Review
  13. Review
  14. The polymorphism of theAnnals of translational medicine · 2021
    Article
  15. Article
  16. Article
  17. Review
  18. Inflammasomes and Type 1 Diabetes.Frontiers in immunology · 2021
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Xiaoxiao SunDepartment of Metabolism and Endocrinology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Ying XiaDepartment of Metabolism and Endocrinology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Yue LiuDepartment of Metabolism and Endocrinology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Yanfei WangDepartment of Metabolism and Endocrinology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Shuoming LuoDepartment of Metabolism and Endocrinology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Jian LinDepartment of Metabolism and Endocrinology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Gan HuangDepartment of Metabolism and Endocrinology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Xia LiDepartment of Metabolism and Endocrinology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Zhiguo XieDepartment of Metabolism and Endocrinology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.ORCID https://orcid.org/0000-0001-5037-3807
Zhiguang ZhouDepartment of Metabolism and Endocrinology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.ORCID https://orcid.org/0000-0002-4451-4906
Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of this study was to clarify the association of two single-nucleotide polymorphisms (SNPs) (rs11651270 and rs2670660) in the MATERIALS AND

methodsA case control study was designed, and participants fulfilling the diagnostic criteria of classical T1D as well as nondiabetic controls were enrolled in the study. The polymorphisms rs11651270 and rs2670660 were genotyped by polymerase chain reaction (PCR) and Sanger sequencing. Chi-squared test and logistic regression analysis were performed to compare the distributions of the allele and genotype between cases and controls. Kruskal-Wallis one-way ANOVA was used to compare the characteristics of different genotypes in participants with T1D.

resultsA total of 510 participants with classical T1D as well as 531 nondiabetic controls were enrolled in the study. The two groups were matched in sex (

conclusionsSNPs in the

Indexed as

Polymorphism, Single NucleotideAdaptor Proteins, Signal TransducingAdolescentAdultAge of OnsetApoptosis Regulatory ProteinsAsian PeopleCase-Control StudiesChinaDiabetes Mellitus, Type 1FemaleGene FrequencyGenetic Predisposition to DiseaseGenotypeHumansMaleAdaptor Proteins, Signal TransducingApoptosis Regulatory ProteinsNLRP1 protein, humanNLR Proteins

Identifiers

PMID31396539
PMCPMC6664699
OpenAlexW2961833818

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.