Evidence map›Paper›PMID 31396400›Full record

ArticleIntegrative food, nutrition and metabolism2019

Modulation of plasma and urine metabolome in colorectal cancer survivors consuming rice bran.

Iman Zarei, Renee C Oppel, Erica C Borresen, Regina J Brown, Elizabeth P Ryan

Open access · diamondAbstract read
In one paragraph

Article in Integrative food, nutrition and metabolism, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Iman ZareiDepartment of Environmental and Radiological Health Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, 80523, USA.
Renee C OppelDepartment of Environmental and Radiological Health Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, 80523, USA.
Erica C BorresenDepartment of Environmental and Radiological Health Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, 80523, USA.
Regina J BrownUniversity of Colorado School of Medicine, Aurora, CO 80045, USA.
Elizabeth P RyanDepartment of Environmental and Radiological Health Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, 80523, USA.
Colorado State University · USUniversity of Colorado Denver · US

Funding

Rice Bran Microbial Metabolism for Colon ChemopreventionR01CA201112 · NCI · COLORADO STATE UNIVERSITY · PI RAINA, KOMAL, RYAN, ELIZABETH P · 2016 to 2020
$1.9M
Dietary Rice Bran Phytochemicals and Microbial Metabolites for Colon ChemopreventR21CA161472 · NCI · COLORADO STATE UNIVERSITY · PI RYAN, ELIZABETH P, WEIR, TIFFANY L · 2012 to 2013
$339k
NCI NIH HHS R01 CA201112NCI NIH HHS R21 CA161472
6 · The paper itself

Abstract

Rice bran has bioactive phytochemicals with cancer protective actions that involve metabolism by the host and the gut microbiome. Globally, colorectal cancer (CRC) is the third leading cause of cancer-related death and the increased incidence is largely attributed to poor dietary patterns, including low daily fiber intake. A dietary intervention trial was performed to investigate the impact of rice bran consumption on the plasma and urine metabolome of CRC survivors. Nineteen CRC survivors participated in a randomized-controlled trial that included consumption of heat-stabilized rice bran (30 g/day) or a control diet without rice bran for 4 weeks. A fasting plasma and first void of the morning urine sample were analyzed by non-targeted metabolomics using ultrahigh-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS). After 4 weeks of either rice bran or control diets, 12 plasma and 16 urine metabolites were significantly different between the groups (

Indexed as

colorectal cancerfood metabolitesmetabolomicsplasmarice branurine

Identifiers

PMID31396400
PMCPMC6687089
OpenAlexW2967372166

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.