ArticleGastroenterology research and practice2019
Prior Appendectomy and the Onset and Course of Crohn's Disease in Chinese Patients.
Article in Gastroenterology research and practice, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed.
- Association of appendectomy with disease phenotype and clinical course in Crohn's disease: results from two cohorts.Techniques in coloproctology · 2025Article
- The Place of Appendicectomy in Inflammatory Bowel Disease-A Review.ANZ journal of surgery · 2025Review
- Early Progression Prediction in Korean Crohn's Disease Using a Korean-Specific PrediXcan Model.International journal of molecular sciences · 2025Article
- Investigating the causal relationship between inflammatory bowel disease and simple appendicitis using Mendelian randomization.Scientific reports · 2024Article
- Mucosa-Associated Lymphoid Tissue Surgeries as a Possible Risk for Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis.Gastroenterology research · 2024Article
- Ileocecal valve that cannot be intubated in Crohn's disease: is this a sign of poor prognosis?International journal of colorectal disease · 2023Article
- Appendix and Ulcerative Colitis: a Key to Explaining the Pathogenesis and Directing Novel Therapies?Inflammatory bowel diseases · 2023Review
- Appendectomy and risk for inflammatory bowel disease: effect of age and time post appendectomy - a cohort study.BMJ open gastroenterology · 2022Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimThe relationship between prior appendectomy and Crohn's disease (CD) has previously revealed conflicting findings. The present study investigates the relationship between prior appendectomy and CD development in Chinese patients.
methodsA retrospective case-control study was performed to compare prior appendectomy rate between CD patients and age- and gender-matched controls at two Chinese hospitals. The clinical course of CD was determined in patients who underwent and did not undergo appendectomies before CD diagnosis.
resultsA total of 617 CD patients and 617 controls were included. The appendectomy rate before CD diagnosis in patients was higher, when compared to controls (6.65% versus 3.73%,
conclusionPrior appendectomy is a risk factor for the onset of CD. However, the appendectomy rate only increased for a short duration before CD diagnosis, likely reflecting a diagnostic bias. Prior appendectomy did not influence the features or course of CD.
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Registered trials
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