Evidence map›Paper›PMID 31396223›Full record

ArticleFrontiers in immunology2019

Composition of the Intestinal Microbiota Determines the Outcome of Virus-Triggered Colitis in Mice.

Silvia Bolsega, Marijana Basic, Anna Smoczek, Manuela Buettner, Claudia Eberl, Daniel Ahrens, Kodwo Appoh Odum, Bärbel Stecher, Andre Bleich

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.

  1. Pooled it
  2. The OMMGut microbes · 2026
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  4. Female-enrichedbioRxiv : the preprint server for biology · 2026
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  5. The Effect ofFoods (Basel, Switzerland) · 2025
    Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Silvia BolsegaHannover Medical School, Institute for Laboratory Animal Science, Hanover, Germany.
Marijana BasicHannover Medical School, Institute for Laboratory Animal Science, Hanover, Germany.
Anna SmoczekHannover Medical School, Institute for Laboratory Animal Science, Hanover, Germany.
Manuela BuettnerHannover Medical School, Institute for Laboratory Animal Science, Hanover, Germany.
Claudia EberlFaculty of Medicine, Max von Pettenkofer Institute of Hygiene and Medical Microbiology, LMU Munich, Munich, Germany.
Daniel AhrensHannover Medical School, Institute for Laboratory Animal Science, Hanover, Germany.
Kodwo Appoh OdumHannover Medical School, Institute for Laboratory Animal Science, Hanover, Germany.
Bärbel StecherFaculty of Medicine, Max von Pettenkofer Institute of Hygiene and Medical Microbiology, LMU Munich, Munich, Germany.
Andre BleichHannover Medical School, Institute for Laboratory Animal Science, Hanover, Germany.
Medizinische Hochschule Hannover · DEGerman Center for Infection Research · DELudwig-Maximilians-Universität München · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The intestinal microbiota is a complex ecosystem implicated in host health and disease. Inflammatory bowel disease (IBD) is a multifactorial chronic disorder of the gastrointestinal mucosa. Even though the exact mechanisms are still unknown, the intestinal microbiota is crucial in IBD development. We previously showed that murine norovirus (MNV) induces colitis in the

Indexed as

AnimalsCaliciviridae InfectionsColitisFemaleGastrointestinal MicrobiomeGerm-Free LifeInterleukin-10MaleMiceMice, KnockoutIL10 protein, mouseInterleukin-10ASFcolitisgnotobiotic modelsIl10-deficient miceintestinal microbiotaMNVOligo-MM12SFB

Identifiers

PMID31396223
PMCPMC6664081
OpenAlexW2956885424

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.