Evidence map›Paper›PMID 31396202›Full record

ArticleFrontiers in immunology2019

14-3-3ζ-A Novel Immunogen Promotes Inflammatory Cytokine Production.

Jenna McGowan, Cara Peter, Saurabh Chattopadhyay, Ritu Chakravarti

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. 14-3-3ζ: A suppressor of inflammatory arthritis.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  6. 14-3-3ζ-TRAF5 axis governs interleukin-17A signaling.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  7. Mechanism and biomarkers in aortitis--a review.Journal of molecular medicine (Berlin, Germany) · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jenna McGowanDepartment of Physiology and Pharmacology, University of Toledo College of Medicine and Life Sciences, Toledo, OH, United States.
Cara PeterDepartment of Physiology and Pharmacology, University of Toledo College of Medicine and Life Sciences, Toledo, OH, United States.
Saurabh ChattopadhyayDepartment of Medical Microbiology and Immunology, University of Toledo College of Medicine and Life Sciences, Toledo, OH, United States.
Ritu ChakravartiDepartment of Physiology and Pharmacology, University of Toledo College of Medicine and Life Sciences, Toledo, OH, United States.
University of Toledo · USUniversity of Toledo Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The presence of autoantibodies against 14-3-3ζ in human autoimmune diseases indicates its antigenic function. However, neither the cause nor the consequence of this newly-identified antigenic function of 14-3-3ζ protein is known. To address this, we investigated the immunological functions of 14-3-3ζ by studying

Indexed as

14-3-3 ProteinsAutoimmune DiseasesHLA-DRB1 ChainsHumansInterferon-gammaTh17 CellsTh1 Cells14-3-3 ProteinsHLA-DRB1*04:01 antigenHLA-DRB1 ChainsIFNG protein, humanInterferon-gammaYWHAZ protein, human14-3-3ζautoantigenHLA-DRB1IL-17Interferon-gammaT cell polarization

Identifiers

PMID31396202
PMCPMC6667649
OpenAlexW2963470576

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.