ArticleFrontiers in microbiology2019
cano-wgMLST_BacCompare: A Bacterial Genome Analysis Platform for Epidemiological Investigation and Comparative Genomic Analysis.
Article in Frontiers in microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
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- Genomic Characterization and Pathogenicity Island Analysis of 17 Mexican Isolates ofCurrent issues in molecular biology · 2026Article
- Whole-genome sequencing ofJournal of medical microbiology · 2026Article
- Genomic Characterization and Antimicrobial Resistance Profile ofAntibiotics (Basel, Switzerland) · 2025Article
- Ceftazidime-avibactam use selects multidrug-resistance and prevents designing collateral sensitivity-based therapies against Pseudomonas aeruginosa.Nature communications · 2025Article
- Multilocus sequence type analysis of coagulase-negative staphylococci from the neonatal intensive care unit of a teaching hospital in Ghana.The Pan African medical journal · 2025Article
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- ProbioMinServer: an integrated platform for assessing the safety and functional properties of potential probiotic strains.Bioinformatics advances · 2023Article
- Comprehensive Assessment of Subtyping Methods for Improved Surveillance of Foodborne Salmonella.Microbiology spectrum · 2022Article
- Comparative in silico characterization of Klebsiella pneumoniae hypervirulent plasmids and their antimicrobial resistance genes.Annals of clinical microbiology and antimicrobials · 2022Article
- Whole-genome sequence analysis through online web interfaces: a review.Genomics & informatics · 2022Article
- Antimicrobial resistance and genomic investigation of non-typhoidalFrontiers in public health · 2022Article
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- Detection and characterization of ESBL-producingPeerJ · 2022Article
- Molecular Identification and Selection of Probiotic Strains Able to Reduce the Serum TMAO Level in Mice Challenged with Choline.Foods (Basel, Switzerland) · 2021Article
- TheMicroorganisms · 2021Article
- Plasmids conferring resistance to extended-spectrum beta-lactamases including a rare IncN+IncR multireplicon carryingOpen research Europe · 2021Article
- Serotyping, MLST, and Core Genome MLST Analysis ofFrontiers in microbiology · 2021Article
- Genomic Investigation of Antimicrobial-ResistantFrontiers in microbiology · 2021Article
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3 authors.
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No grant is acknowledged in the PubMed record.
Abstract
With the decreasing cost of next-generation sequencing, whole-genome sequence-based bacterial genome comparisons are expected to become a mainstream process in the public health domain. Extended multilocus sequence typing (MLST) methods are becoming increasingly popular for use in comparing bacterial genetic relatedness in epidemiological investigations. Several extended MLST schemes based on biological signatures have been reported. Among them, whole-genome MLST (wgMLST) has gradually become one of the most widely used approaches for bacterial strain typing. In addition to using bacterial typing, many researchers aim to identify differences in the genes of compared strains. Because these differences might provide insights into critical bacterial functions, such as virulence and pathogenicity, researchers usually study these genes that differ between strains. Hence, we designed a web service tool based on wgMLST-constructed tree topology coupled with the feature selection method to create the "canonical wgMLST (cano-wgMLST) tree." The genes that differ between strains are shown at each split of the tree, thereby directly providing information for performing a comparative genomic analysis for each strain pair. We demonstrated that this web service tool could be operated efficiently on two datasets consisting of 22
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