Evidence map›Paper›PMID 31396164›Full record

ArticleFrontiers in microbiology2019

Enhancing Recombinant Protein Yields in the

Alexandros Karyolaimos, Henry Ampah-Korsah, Tamara Hillenaar, Anna Mestre Borras, Katarzyna Magdalena Dolata, Susanne Sievers, Katharina Riedel, Robert Daniels, Jan-Willem de Gier

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 61 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Engineering PET surface colonization with a synthetic bacterial consortium.Frontiers in bioengineering and biotechnology · 2026
    Article
  7. Papain expression in theApplied and environmental microbiology · 2025
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Competing stress-dependent oligomerization pathways regulate self-assembly of the periplasmic protease-chaperone DegP.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  14. Strategies to Enhance Periplasmic Recombinant Protein Production Yields inFrontiers in bioengineering and biotechnology · 2021
    Review
  15. Article
  16. Article
  17. Evolution ofInternational journal of molecular sciences · 2020
    Review
  18. Functional mononuclear molybdenum enzymes: challenges and triumphs in molecular cloning, expression, and isolation.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2020
    Review
  19. Article
  20. An Engineered Pathway for Production of Terminally SialylatedFrontiers in bioengineering and biotechnology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Alexandros KaryolaimosDepartment of Biochemistry and Biophysics, Center for Biomembrane Research, Stockholm University, Stockholm, Sweden.
Henry Ampah-KorsahDepartment of Biochemistry and Biophysics, Center for Biomembrane Research, Stockholm University, Stockholm, Sweden.
Tamara HillenaarDepartment of Biochemistry and Biophysics, Center for Biomembrane Research, Stockholm University, Stockholm, Sweden.
Anna Mestre BorrasDepartment of Biochemistry and Biophysics, Center for Biomembrane Research, Stockholm University, Stockholm, Sweden.
Katarzyna Magdalena DolataInstitute of Microbiology, University of Greifswald, Greifswald, Germany.
Susanne SieversInstitute of Microbiology, University of Greifswald, Greifswald, Germany.
Katharina RiedelInstitute of Microbiology, University of Greifswald, Greifswald, Germany.
Robert DanielsDepartment of Biochemistry and Biophysics, Center for Biomembrane Research, Stockholm University, Stockholm, Sweden.
Jan-Willem de GierDepartment of Biochemistry and Biophysics, Center for Biomembrane Research, Stockholm University, Stockholm, Sweden.
Stockholm University · SEUniversität Greifswald · DE

Funding

NIAID NIH HHS HHSN272201400005C
6 · The paper itself

Abstract

Proteins that contain disulfide bonds mainly mature in the oxidative environment of the eukaryotic endoplasmic reticulum or the periplasm of Gram-negative bacteria. In

Indexed as

Escherichia coliperiplasmprotein production rateprotein production screenrecombinant proteinsignal peptide

Identifiers

PMID31396164
PMCPMC6664373
OpenAlexW2964298233

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.