ReviewFrontiers in endocrinology2019
Application of Growth Hormone in
Review in Frontiers in endocrinology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05281341 (Effect of Growth Hormone Administration With Controlled Ovarian Stimulation in Expected Poor Responders POSEIDON Group 3 and 4 Undergoing ICSI Using Antagonist Protocol), which is not on this map. Cited by 24 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Growth Hormone Administration With Controlled Ovarian Stimulation in Expected Poor Responders POSEIDON Group 3 and 4 Undergoing ICSI Using Antagonist Protocol
Who cites it
24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 55 citations in OpenAlex.
- The efficacy of adjuvant therapies in improving endometrial function of women undergoing assisted reproductive technology: a systematic review and network meta-analysis.BMC pregnancy and childbirth · 2025Pooled it
- Growth hormone improves the pregnancy outcomes in poor ovarian responders undergoing in vitro fertilization: an umbrella review.Journal of assisted reproduction and genetics · 2025Pooled it
- Meta-analysis of intrauterine hCG perfusion efficacy in recurrent implantation failure as defined by ESHRE guidelines.BMC pregnancy and childbirth · 2024Pooled it
- Article
- Growth Hormone Improves Ovarian Follicle Health in Premature Ovarian Failure Mice by Reducing Apoptosis : (GH Improves Ovarian Follicle Health in POF Mice by Reducing Apoptosis).Reproductive sciences (Thousand Oaks, Calif.) · 2025Article
- Growth hormone reduces aneuploidy and improves oocytes quality by JAK2-MAPK3/1 pathway in aged mice.Journal of translational medicine · 2023Article
- Hyperbaric Oxygen Treatment Ameliorates the Decline in Oocyte Quality and Improves the Fertility of Aged Female Mice.Reproductive sciences (Thousand Oaks, Calif.) · 2023Article
- The effect of growth hormone on the metabolome of follicular fluid in patients with diminished ovarian reserve.Reproductive biology and endocrinology : RB&E · 2023Observational
- The effect of growth hormone on ovarian function recovery in a mouse model of ovarian insufficiency.Frontiers in endocrinology · 2023Article
- The Effect of Human Growth Hormone on Endometrial Growth in Controlled Ovarian Hyperstimulation Cycles.Journal of personalized medicine · 2022Article
- The Clinical Application of Growth Hormone and Its Biological and Molecular Mechanisms in Assisted Reproduction.International journal of molecular sciences · 2022Review
- Effects of Adjuvant Growth Hormone Therapy on Poor Ovarian Responders in Assisted Reproductive Technology.Maedica · 2022Article
- Importance of IGF-I levels in IVF: potential relevance for growth hormone (GH) supplementation.Journal of assisted reproduction and genetics · 2022Article
- New insight into the importance of formulation variables on parenteral growth hormone preparations: potential effect on the injection-site pain.Frontiers in endocrinology · 2022Review
- Endocrine disorders and fertility and pregnancy: An update.Frontiers in endocrinology · 2022Review
- Aging conundrum: A perspective for ovarian aging.Frontiers in endocrinology · 2022Review
- Effects of growth hormone co-treatment on in vitro fertilization outcomes in women with expected normal ovarian responseTurkish journal of obstetrics and gynecology · 2021Article
- Towards Personalized Antioxidant Use in Female Infertility: Need for More Molecular and Clinical Studies.Biomedicines · 2021Review
- Recent trends in therapeutic strategies for repairing endometrial tissue in intrauterine adhesion.Biomaterials research · 2021Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Growth hormone (GH) is a peptide hormone secreted mainly by the anterior part of the pituitary gland and plays a critical role in cell growth, development, and metabolism throughout the body. GH can not only directly influence human oocytes and cumulus cells but also indirectly improve oocyte quality through activating synthesis of insulin-like growth factor-I or promoting follicle-stimulating hormone-induced ovarian steroidogenesis. Since GH can regulate female and male infertility, it has been applied in the management of infertility for many years, especially in patients with poor ovarian response or poor prognosis. During ovarian stimulation, GH administration might improve the success rate of
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.