ReviewFrontiers in endocrinology2019
Modulatory Effects of Plant Polyphenols on Bone Remodeling: A Prospective View From the Bench to Bedside.
Review in Frontiers in endocrinology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 55 citations in OpenAlex.
- Yerba Mate and Bone Health: Can Antioxidant Capacity Influence Skeletal Outcomes?Journal of bone metabolism · 2026Article
- Article
- Article
- Effects of Rosmarinic Acid and Sinapic Acid on the Skeletal System in Ovariectomized Rats.Nutrients · 2026Article
- Anti-Inflammatory and bone-protective effects of Pimpinella brachycarpa extract in a rat periodontitis model.Journal of molecular histology · 2026Article
- Article
- Electrospun PCL Mats Modified with Magnetic Nanoparticles and Tannic Acid with Antibacterial and Possible Antiosteosarcoma Activity for Bone Tissue Engineering and Cancer Treatment.ACS biomaterials science & engineering · 2025Article
- The Preventive Impact of Chokeberry (Nutrients · 2025Article
- Increased Osteoblastic and Osteocytic in Vitro Cell Viability by Yerba Mate (Ilex paraguariensis).Journal of bone metabolism · 2024Article
- Iris Koreana NAKAI Inhibits Osteoclast Formation via p38-Mediated Nuclear Factor of Activated T Cells 1 Signaling Pathway.Journal of bone metabolism · 2023Article
- New Insights into Nutrients for Bone Health and Disease.Nutrients · 2023Article
- Review
- Association between Phytochemical Index and Osteoporosis in Women: A Prospective Cohort Study in Korea.Nutrients · 2023Article
- Oxidative Stress and Natural Antioxidants in Osteoporosis: Novel Preventive and Therapeutic Approaches.Antioxidants (Basel, Switzerland) · 2023Review
- Research progress and future prospects of antimicrobial modified polyetheretherketone (PEEK) for the treatment of bone infections.Frontiers in bioengineering and biotechnology · 2023Review
- Polyphenolic Compounds Inhibit Osteoclast Differentiation While Reducing Autophagy through Limiting ROS and the Mitochondrial Membrane Potential.Biomolecules · 2022Article
- Osteogenic Effect of Fisetin Doping in Bioactive Glass/Poly(caprolactone) Hybrid Scaffolds.ACS omega · 2022Article
- Green-Synthesized Magnesium Hydroxide Nanoparticles Induced Osteoblastic Differentiation in Bone Co-Cultured Cells.Pharmaceuticals (Basel, Switzerland) · 2021Article
- Polyphenols-loaded electrospun nanofibers in bone tissue engineering and regeneration.Biomaterials research · 2021Review
- Rosehip Extract-Functionalized Magnesium Hydroxide Nanoparticles and Its Effect on Osteoblastic and Osteoclastic Cells.Materials (Basel, Switzerland) · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
During the past, a more comprehensive knowledge of mechanisms implicated in bone resorption processes has driven researchers to develop a compound library of many small molecules that specifically interfere with the genesis of osteoclast precursors cells. Natural compounds that suppress osteoclast commitment may have therapeutic value in treating pathologies associated with bone resorption like osteoporosis, rheumatoid arthritis, bone metastasis, and periodontal disease. The present review is focused on the current knowledge on the polyphenols derived from plants that could be efficacious in suppressing osteoclast differentiation and bone resorption.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.