Evidence map›Paper›PMID 31396154›Full record

SynthesisFrontiers in endocrinology2019

A Systematic Review and Meta-Analysis of Patient Preferences for Combination Thyroid Hormone Treatment for Hypothyroidism.

Amit Akirov, Rouhi Fazelzad, Shereen Ezzat, Lehana Thabane, Anna M Sawka

Open access · goldAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Frontiers in endocrinology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 3 pooled it
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 36 citations in OpenAlex.

  1. Treatment Preferences in Patients With Hypothyroidism.The Journal of clinical endocrinology and metabolism · 2025
    Pooled it
  2. Pooled it
  3. Guideline
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Critical Approach to Hypothyroid Patients With Persistent Symptoms.The Journal of clinical endocrinology and metabolism · 2023
    Article
  10. Review
  11. Review
  12. Optimal Thyroid Hormone Replacement.Endocrine reviews · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Liothyronine and Desiccated Thyroid Extract in the Treatment of Hypothyroidism.Thyroid : official journal of the American Thyroid Association · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Amit AkirovDepartment of Endocrine Oncology, Princess Margaret Cancer Centre, Toronto, ON, Canada.
Rouhi FazelzadPrincess Margaret Cancer Centre, University Health Network Library and Information Services, Toronto, ON, Canada.
Shereen EzzatDepartment of Endocrine Oncology, Princess Margaret Cancer Centre, Toronto, ON, Canada.
Lehana ThabaneDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada.
Anna M SawkaDivision of Endocrinology, University Health Network and University of Toronto, Toronto, ON, Canada.
Princess Margaret Cancer Centre · CAImpact · CAUniversity Health Network · CAUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

hypothyroidismlevothyroxinemeta-analysisrandomized controlled trialssystematic reviewthyroid hormonetriiodothyronine

Identifiers

PMID31396154
PMCPMC6667836
OpenAlexW2962889256

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.