Evidence map›Paper›PMID 31396055›Full record

ArticleFrontiers in cellular neuroscience2019

GABA Regulation of Burst Firing in Hippocampal Astrocyte Neural Circuit: A Biophysical Model.

Junxiu Liu, Liam McDaid, Alfonso Araque, John Wade, Jim Harkin, Shvan Karim, David C Henshall, Niamh M C Connolly, Anju P Johnson, Andy M Tyrrell and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 3 countries.

Junxiu LiuSchool of Computing, Engineering and Intelligent Systems, Ulster University, Derry, United Kingdom.
Liam McDaidSchool of Computing, Engineering and Intelligent Systems, Ulster University, Derry, United Kingdom.
Alfonso AraqueDepartment of Neuroscience, University of Minnesota, Minneapolis, MN, United States.
John WadeSchool of Computing, Engineering and Intelligent Systems, Ulster University, Derry, United Kingdom.
Jim HarkinSchool of Computing, Engineering and Intelligent Systems, Ulster University, Derry, United Kingdom.
Shvan KarimSchool of Computing, Engineering and Intelligent Systems, Ulster University, Derry, United Kingdom.
David C HenshallDepartment of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland.
Niamh M C ConnollyDepartment of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland.
Anju P JohnsonDepartment of Electronic Engineering, University of York, York, United Kingdom.
Andy M TyrrellDepartment of Electronic Engineering, University of York, York, United Kingdom.
Jon TimmisDepartment of Electronic Engineering, University of York, York, United Kingdom.
Alan G MillardDepartment of Electronic Engineering, University of York, York, United Kingdom.
James HilderDepartment of Electronic Engineering, University of York, York, United Kingdom.
David M HallidayDepartment of Electronic Engineering, University of York, York, United Kingdom.
University of York · GBUniversity of Ulster · GBRoyal College of Surgeons in Ireland · IEUniversity of Minnesota · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is now widely accepted that glia cells and gamma-aminobutyric acidergic (GABA) interneurons dynamically regulate synaptic transmission and neuronal activity in time and space. This paper presents a biophysical model that captures the interaction between an astrocyte cell, a GABA interneuron and pre/postsynaptic neurons. Specifically, GABA released from a GABA interneuron triggers in astrocytes the release of calcium (

Indexed as

astrocyte cellburst firingcalcium oscillationGABA interneuronpotentiation

Identifiers

PMID31396055
PMCPMC6664076
OpenAlexW2958926595

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.