Evidence map›Paper›PMID 31396049›Full record

ArticleFrontiers in molecular neuroscience2019

Neurobiology and Therapeutic Potential of α5-GABA Type A Receptors.

Tija C Jacob

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed, 1 pooled it
6.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 1 synthesis or guideline pooled it, 119 citations in OpenAlex.

  1. Cys-loop receptors on cannabinoids: All high?Frontiers in physiology · 2022
    Pooled it
  2. Effects of diazepam on hippocampal blood flow in people at clinical high risk for psychosis.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
    Trial
  3. Article
  4. Article
  5. The role of GABANeuroscience and biobehavioral reviews · 2026
    Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. αJournal of psychopharmacology (Oxford, England) · 2026
    Article
  14. RO4938581, a GABAMolecular psychiatry · 2026
    Article
  15. Restoration of Extrasynaptic/Synaptic GABANeuroscience bulletin · 2026
    Article
  16. Negative allosteric modulation of α5-GABAbioRxiv : the preprint server for biology · 2026
    Article
  17. GABADrug design, development and therapy · 2026
    Review
  18. Review
  19. Article
  20. Article

9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Tija C JacobDepartment of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States.
University of Pittsburgh · US

Funding

Benzodiazepine treatment induced neuroplasticityR01MH114908 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JACOB, TIJA C. · 2019 to 2022
$1.6M
NIMH NIH HHS R01 MH114908
6 · The paper itself

Abstract

α5 subunit containing GABA type A receptors (GABA

Indexed as

alpha 5 subunitautismcognitiondevelopmentGABA A receptormemorynegative and positive allosteric modulators

Identifiers

PMID31396049
PMCPMC6668551
OpenAlexW2960913096

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.