Trial reportNutrition & diabetes2019
Impact of energy turnover on the regulation of glucose homeostasis in healthy subjects.
Trial report in Nutrition & diabetes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 22 citations in OpenAlex.
- Use of Continuous Glucose Monitors in Exercise Research Studies-A Scoping Review on Study Characteristics and Common Practices.Sports (Basel, Switzerland) · 2026Review
- Effects of Sodium Acetate and Sodium Butyrate on the Volatile Compounds in Mare's Milk Based on GC-IMS Analysis.Animals : an open access journal from MDPI · 2025Article
- Article
- Continuous Glucose Profiles in Healthy People With Fixed Meal Times and Under Everyday Life Conditions.Journal of diabetes science and technology · 2024Article
- Machine learning and molecular dynamics simulations predict potential TGR5 agonists for type 2 diabetes treatment.Frontiers in chemistry · 2024Article
- Recharacterizing the Metabolic State of Energy Balance in Thrifty and Spendthrift Phenotypes.The Journal of clinical endocrinology and metabolism · 2020Article
- Detection and Independent Validation of Model-Based Quantitative Transcriptional Regulation Relationships Altered in Lung Cancers.Frontiers in bioengineering and biotechnology · 2020Article
Corrections and comments
- Erratum issued
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveSedentary lifestyle increases the risk of type 2 diabetes. The aim of this study was to investigate the impact of different levels of energy turnover (ET; low, medium, and high level of physical activity and the corresponding energy intake) on glucose metabolism at zero energy balance, caloric restriction, and overfeeding.
methodsSixteen healthy individuals (13 men, 3 women, 25.1 ± 3.9 years, BMI 24.0 ± 3.2 kg/m
resultsDaylong glycemia and insulin secretion did not increase with higher ET at all conditions of energy balance (EB, CR, and OF), despite a correspondingly higher CHO intake (Δ low vs. high ET: +86 to 135 g of CHO/d). At CR, daylong glycemia (p = 0.02) and insulin secretion (p = 0.04) were even reduced with high compared with low ET. HOMA-IR was impaired with OF and improved with CR, whereas ET had no effect on fasting insulin sensitivity. A higher ET led to lower postprandial glucose and insulin levels under conditions of CR and OF.
conclusionLow-intensity physical activity can significantly improve postprandial glycemic response of healthy individuals, independent of energy balance.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.