Evidence map›Paper›PMID 31395845›Full record

ArticleMicromachines2019

A Wireless Implantable System for Facilitating Gastrointestinal Motility.

Po-Min Wang, Genia Dubrovsky, James C Y Dunn, Yi-Kai Lo, Wentai Liu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Micromachines, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Po-Min WangDepartment of Bioengineering, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Genia DubrovskyDivision of Pediatric Surgery, Department of Surgery, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.
James C Y DunnDepartment of Bioengineering, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Yi-Kai LoNiche Biomedical Inc., Los Angeles, CA 90095, USA.
Wentai LiuDepartment of Bioengineering, University of California, Los Angeles, Los Angeles, CA 90095, USA. wentai@ucla.edu.

Funding

Endowment of California Capital Equity LLC N/ANational Science Foundation 1647917
6 · The paper itself

Abstract

Gastrointestinal (GI) electrical stimulation has been shown in several studies to be a potential treatment option for GI motility disorders. Despite the promising preliminary research progress, however, its clinical applicability and usability are still unknown and limited due to the lack of a miniaturized versatile implantable stimulator supporting the investigation of effective stimulation patterns for facilitating GI dysmotility. In this paper, we present a wireless implantable GI modulation system to fill this technology gap. The system consists of a wireless extraluminal gastrointestinal modulation device (EGMD) performing GI electrical stimulation, and a rendezvous device (RD) and a custom-made graphical user interface (GUI) outside the body to wirelessly power and configure the EGMD to provide the desired stimuli for modulating GI smooth muscle activities. The system prototype was validated in bench-top and in vivo tests. The GI modulation system demonstrated its potential for facilitating intestinal transit in the preliminary in vivo chronic study using porcine models.

Indexed as

bioelectronics medicineelectroceuticalsgastrointestinal stimulationimplantmotilityneuromodulation

Identifiers

PMID31395845
PMCPMC6722874

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.