Evidence map›Paper›PMID 31395834›Full record

ArticleMarine drugs2019

Bioactive Brominated Oxindole Alkaloids from the Red Sea Sponge

Seham S El-Hawary, Ahmed M Sayed, Rabab Mohammed, Hossam M Hassan, Mostafa E Rateb, Elham Amin, Tarek A Mohammed, Mohamed El-Mesery, Abdullatif Bin Muhsinah, Abdulrhman Alsayari and 3 more

Abstract read
In one paragraph

Article in Marine drugs, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Metabolomic profiling ofRSC advances · 2024
    Article
  10. Red Sea SpongeOncoTargets and therapy · 2024
    Article
  11. Article
  12. Review
  13. Metabolites · 2023
    Review
  14. Naturally Occurring Organohalogen Compounds-A Comprehensive Review.Progress in the chemistry of organic natural products · 2023
    Review
  15. Review
  16. Review
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Seham S El-HawaryDepartment of Pharmacognosy, Faculty of Pharmacy, Cairo University, 11787 Cairo, Egypt.
Ahmed M SayedDepartment of Pharmacognosy, Faculty of Pharmacy, Nahda University, 62513 Beni-Suef, Egypt.ORCID 0000-0002-1442-183X
Rabab MohammedDepartment of Pharmacognosy, Faculty of Pharmacy, Beni-Suef University, 62514 Beni-Suef, Egypt.
Hossam M HassanDepartment of Pharmacognosy, Faculty of Pharmacy, Beni-Suef University, 62514 Beni-Suef, Egypt.ORCID 0000-0003-0174-4434
Mostafa E RatebDepartment of Pharmacognosy, Faculty of Pharmacy, Beni-Suef University, 62514 Beni-Suef, Egypt.ORCID 0000-0003-4043-2687
Elham AminDepartment of Pharmacognosy, Faculty of Pharmacy, Beni-Suef University, 62514 Beni-Suef, Egypt.ORCID 0000-0002-7190-3974
Tarek A MohammedMarine Invertebrates, National Institute of Oceanography and Fisheries, Red Sea Branch, 84511 Hurghada, Egypt.
Mohamed El-MeseryDivision of Molecular Internal Medicine, Department of Internal Medicine II, University Hospital Würzburg, Grombühlstr. 12, 97080 Würzburg, Germany.
Abdullatif Bin MuhsinahDepartment of Pharmacognosy, College of Pharmacy, King Khalid University, Abha 61441, Saudi Arabia.
Abdulrhman AlsayariDepartment of Pharmacognosy, College of Pharmacy, King Khalid University, Abha 61441, Saudi Arabia.
Harald WajantDivision of Molecular Internal Medicine, Department of Internal Medicine II, University Hospital Würzburg, Grombühlstr. 12, 97080 Würzburg, Germany.
Mohamed A AnanyDivision of Molecular Internal Medicine, Department of Internal Medicine II, University Hospital Würzburg, Grombühlstr. 12, 97080 Würzburg, Germany. mohamed_M@klinik.uni-wuerzburg.de.
Usama Ramadan AbdelmohsenDepartment of Pharmacognosy, Faculty of Pharmacy, Minia University, 61519 Minia, Egypt. usama.ramadan@mu.edu.eg.ORCID 0000-0002-1014-6922

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the present study, LC-HRESIMS-assisted dereplication along with bioactivity-guided isolation led to targeting two brominated oxindole alkaloids (compounds

Indexed as

AlkaloidsAnimalsAnti-Infective AgentsAntiprotozoal AgentsBacteriaBiofilmsCallyspongiaCell Line, TumorHalogenationHT29 CellsHumansIndian OceanMicrobial Sensitivity TestsOxindolesAlkaloidsAnti-Infective AgentsAntiprotozoal AgentsOxindolesantibacterialantibiofilmanticancerantitrypanosomalCallyspongia siphonellaLC-HRESIMSmetabolomic profilingoxindole alkaloidstisindoline

Identifiers

PMID31395834
PMCPMC6723499

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.