Evidence map›Paper›PMID 31395791›Full record

ArticleAging2019

Sex differences in the associations of placental epigenetic aging with fetal growth.

Fasil Tekola-Ayele, Tsegaselassie Workalemahu, Gezahegn Gorfu, Deepika Shrestha, Benjamin Tycko, Ronald Wapner, Cuilin Zhang, Germaine M Buck Louis

Open access · greenAbstract read
In one paragraph

Article in Aging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 1 pooled it
20.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 1 synthesis or guideline pooled it, 88 citations in OpenAlex.

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  19. Maternal Nutrition, Toxicants, and Epigenetic Programming of Obesity Across Generations.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 3 countries.

Fasil Tekola-AyeleEpidemiology Branch, Division of Intramural Population Health Research, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.
Tsegaselassie WorkalemahuEpidemiology Branch, Division of Intramural Population Health Research, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.
Gezahegn GorfuDepartment of Clinical Laboratory Science, College of Nursing and Allied Health Sciences, Howard University, Washington, DC 20059, USA.
Deepika ShresthaEpidemiology Branch, Division of Intramural Population Health Research, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.
Benjamin TyckoHackensack-Meridian Health Center for Discovery and Innovation and the Hackensack-Meridian Health School of Medicine at Seton Hall University, Nutley, NJ, 07110, USA.
Ronald WapnerDepartment of Obstetrics and Gynecology, Columbia University, New York, NY 10032, USA.
Cuilin ZhangEpidemiology Branch, Division of Intramural Population Health Research, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.
Germaine M Buck LouisDean's Office, College of Health and Human Services, George Mason University, Fairfax, VA 22030, USA.
Eunice Kennedy Shriver National Institute of Child Health and Human Development · USColumbia University · USGeorge Mason University · USHackensack Meridian Health · USHoward University · USNational Institute of Child Health · HUNational Institutes of Health · US

Funding

Genetic epidemiology of early growth and cardiometabolic diseasesZIAHD008967 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI TEKOLA-AYELE, FASIL · 2018 to 2025
$4.4M
NICHD NIH HHS HHSN275200800001CNICHD NIH HHS HHSN275200800012CNICHD NIH HHS HHSN275200800013CNICHD NIH HHS HHSN275201000009C
6 · The paper itself

Abstract

Identifying factors that influence fetal growth in a sex-specific manner can help unravel mechanisms that explain sex differences in adverse neonatal outcomes and

Indexed as

AdultAnthropometryBirth WeightDNA MethylationEpigenesis, GeneticFemaleFetal DevelopmentHeadHumansInfant, Low Birth WeightInfant, NewbornInfant, Small for Gestational AgeMalePlacentationPregnancyPregnancy Outcomedevelopmental origins of health and disease (DOHaD)epigenetic clockfetal growthplacental agingsex differences

Identifiers

PMID31395791
PMCPMC6710059
OpenAlexW2968484619

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.