Evidence map›Paper›PMID 31395683›Full record

ArticleMolecular cancer therapeutics2019

Leelamine Is a Novel Lipogenesis Inhibitor in Prostate Cancer Cells

Krishna B Singh, Eun-Ryeong Hahm, Subrata K Pore, Shivendra V Singh

Open access · bronzeAbstract read
In one paragraph

Article in Molecular cancer therapeutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Article
  3. Iterative One-Carbon Homologation of Unmodified Carboxylic Acids.Journal of the American Chemical Society · 2024
    Article
  4. Emerging roles of the chromatin remodeler MORC2 in cancer metabolism.Medical oncology (Northwood, London, England) · 2024
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Leelamine suppresses cMyc expression in prostate cancer cellsJournal of cancer metastasis and treatment · 2021
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Krishna B SinghDepartment of Pharmacology & Chemical Biology, and UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Eun-Ryeong HahmDepartment of Pharmacology & Chemical Biology, and UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Subrata K PoreDepartment of Pharmacology & Chemical Biology, and UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.ORCID 0000-0002-6324-6994
Shivendra V SinghDepartment of Pharmacology & Chemical Biology, and UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania. singhs@upmc.edu.
UPMC Hillman Cancer Center · US

Funding

VECTOR CORE FACILITYP30CA047904 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Jessie Nedrow · 1988 to 2026
$158.0M
Anticarcinogenic Effect of ITCs Against Prostate CancerR01CA101753 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SINGH, SHIVENDRA · 2003 to 2019
$4.9M
Biomarkers of Sulforaphane/Broccoli Sprout Extract in Prostate CancerR01CA225716 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SINGH, SHIVENDRA · 2019 to 2023
$2.8M
NCI NIH HHS P30 CA047904NCI NIH HHS R01 CA101753NCI NIH HHS R01 CA225716
6 · The paper itself

Abstract

Increased

Indexed as

AbietanesATP Citrate (pro-S)-LyaseCell Line, TumorCeruletideDown-RegulationFatty Acids, NonesterifiedHumansLipid DropletsLipogenesisMaleNeoplasm ProteinsProstateProstatic NeoplasmsReceptors, AndrogenRNA, MessengerSterol Regulatory Element Binding Protein 1AbietanesAR protein, humanATP Citrate (pro-S)-LyaseCeruletidedehydroabietylamineFatty Acids, NonesterifiedNeoplasm ProteinsReceptors, AndrogenRNA, MessengerSREBF1 protein, humanSterol Regulatory Element Binding Protein 1

Identifiers

PMID31395683
PMCPMC6774899
OpenAlexW2969100744

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.